@misc{10481/93670,
year = {2024},
month = {5},
url = {https://hdl.handle.net/10481/93670},
abstract = {During the last decades, endocrine-disrupting chemicals (EDCs) have attracted the attention
of the scientific community, as a result of a deepened understanding of their effects on human health.
These compounds, which can reach populations through the food chain and a number of daily life
products, are known to modify the activity of the endocrine system. Regarding vulnerable groups
like pregnant mothers, the potential damage they can cause increases their importance, since it is the
health of two lives that is at risk. EDCs can affect the gestation process, altering fetal development, and
eventually inducing the appearance of many disorders in their childhood and/or adulthood. Because
of this, several of these substances have been studied to clarify the influence of their prenatal exposure
on the cognitive and psychomotor development of the newborn, together with the appearance of
non-communicable diseases and other disorders. The most novel research on the subject has been
gathered in this narrative review, with the aim of clarifying the current knowledge on the subject.
EDCs have shown, through different studies involving both animal and human investigation, a
detrimental effect on the development of children exposed to the during pregnancy, sometimes with
sex-specific outcomes. However, some other studies have failed to find these associations, which
highlights the need for deeper and more rigorous research, that will provide an even more solid
foundation for the establishment of policies against the extended use of these chemicals.},
organization = {Ph.D. Excellence Program “Nutrición y
Ciencias de los Alimentos” from the University of Granada},
organization = {FPU21/04865 funded by the Ministry of Education of Spain},
publisher = {MDPI},
keywords = {endocrine-disrupting chemical},
keywords = {newborn},
keywords = {non communicable diseases},
title = {Implications of Prenatal Exposure to Endocrine-Disrupting Chemicals in Offspring Development: A Narrative Review},
doi = {10.3390/nu16111556},
author = {Toledano, Juan M. and Puche Juárez, María and Moreno Fernández, Jorge and González-Palacios, Patricia and Rivas Velasco, Ana María and Ochoa Herrera, Julio José and Díaz Castro, Javier},
}