@misc{10481/93411,
year = {2024},
month = {5},
url = {https://hdl.handle.net/10481/93411},
abstract = {This study investigates the encapsulation of Tenebrio molitor hydrolysate exhibiting DPP-IV
inhibitory activity by spray-drying and electrospraying techniques. First, we optimized the feed formulation
and processing conditions required to obtain nano-microcapsules by electrospraying when using
Arabic gum as an encapsulating agent and pullulan and Tween 20 as additives. The optimum formulation
was also dried by spray-drying, where the removal of the additives was also assayed. Morphology
analysis reveals that electrosprayed capsules have a smaller size (1.2   0.5  m vs. 12.4   8.7  m) and
greater uniformity compared to those obtained by spray-drying. Regarding the surface nitrogen content
and DPP-IV inhibitory activity, our results show no significant difference between the electrosprayed
capsules and spray-dried capsules containing additives (IC50 of ~1.5 mg protein/mL). Therefore, it was
concluded that adding additives during spray-drying allows for a similar encapsulation efficiency
and reduced degradation during processing, as achieved by electrospraying technique but providing
higher productivity. On the other hand, spray-dried capsules without additives displayed a higher
surface nitrogen content percentage, which was mainly due to the absence of Tween 20 in the feed
formulation. Consequently, these capsules presented a higher IC50 value (IC50 of 1.99   0.03 mg
protein/mL) due to the potential degradation of surface-exposed peptides.},
organization = {PID2020-114137RB-I00 funded by
MCIN/AEI/10.13039/501100011033},
publisher = {MDPI},
keywords = {Antidiabetic peptides},
keywords = {Enzymatic hydrolysis},
keywords = {Nano-microencapsulation},
title = {Encapsulation of Tenebrio molitor Hydrolysate with DPP-IV Inhibitory Activity by Electrospraying and Spray-Drying},
doi = {10.3390/nano14100840},
author = {Berraquero García, Carmen and Martínez-Sánchez, Lydia and Guadix Escobar, Emilia María and García Moreno, Pedro Jesús},
}