@misc{10481/93396,
year = {2024},
month = {5},
url = {https://hdl.handle.net/10481/93396},
abstract = {Cereal grains play an important role in human health as a source of macro- and micronutrients, besides
phytochemicals. The metabolite diversity was investigated in cereal crops and their milling fractions by untargeted metabolomics
ultra-high-performance liquid chromatography−tandem mass spectrometry (UHPLC−MS/MS) of 69 samples: 7 species (barley,
oat, pearl millet, rye, sorghum, triticale, and wheat), 23 genotypes, and 4 milling fractions (husk, bran, flour, and wholegrain).
Samples were also analyzed by in vitro antioxidant activity. UHPLC−MS/MS signals were processed using XCMS, and metabolite
annotation was based on SIRIUS and GNPS libraries. Bran and husk showed the highest antioxidant capacity and phenolic content/
diversity. The major metabolite classes were phenolic acids, flavonoids, fatty acyls, and organic acids. Sorghum, millet, barley, and
oats showed distinct metabolite profiles, especially related to the bran fraction. Molecular networking and chemometrics provided a
comprehensive insight into the metabolic profiling of cereal crops, unveiling the potential of coproducts and super cereals such as
sorghum and millet as sources of polyphenols.},
organization = {Foundation for the Research
Support of the State of Rio de Janeiro (FAPERJ) (26/
010.100988/2018; E-26/210.716/2021; E-26/010.001294/
2019; E-26/201.317/2022; E-26/210.152/2023)},
organization = {National
Council for Scientific and Technological Development (CNPq)
(310343/2019−4; 407350/2023−3)},
organization = {Coordination for
Improvement of Personnel with Higher Education (CAPES)
(financial code 001) and supported by UNIRIO},
organization = {Coordination for the Improvement
of Higher Education Personnel - CAPES (ROR identifier:
00x0ma614)},
publisher = {ACS Publications},
keywords = {Cereal coproducts},
keywords = {Metabolomics},
keywords = {Multivariate data analysis},
title = {Overview of the Metabolite Composition and Antioxidant Capacity of Seven Major and Minor Cereal Crops and Their Milling Fractions},
doi = {10.1021/acs.jafc.4c01312},
author = {Ribeiro da Silva Lima, Luciana and Barros Santos, Millena C. and P. Gomes, Paulo Wender and Fernández Ochoa, Álvaro and Larraz Ferreira, Mariana Simões},
}