@misc{10481/93034,
year = {2024},
month = {4},
url = {https://hdl.handle.net/10481/93034},
abstract = {The development of new biocompatible and eco-friendly materials is essential for the future of dental practice,
especially for the management of dental caries. In this study, a novel and simple method was applied for the
green synthesis of silver nanoparticles (AgNPs) from the aqueous extract of Camellia sinensis (WT) and functionalized
with chitosan (CHS) and NaF. The effects of WT_AgNPs application on demineralized dentin were
evaluated for potential dental applications. The WT_AgNPs showed molecular groups related to organic compounds,
potentially acting as reducing and capping agents. All AgNPs presented spherical shapes with crystal
sizes of approximately 20 nm. Forty human molars were assigned to control: sound (SD) and demineralised
dentine (DD), and experimental groups: WT_AgNPs, WT_AgNPs_NaF, and WT_AgNPs_CHS. Then, the NPs were
applied to DD to evaluate the chemical, crystallographic, and microstructural characteristics of treated-dentine.
In addition, a three-point bending test was employed to assess mechanical response. The application of
WT_AgNPs indicated a higher mineralisation degree and crystallites sizes of hydroxyapatite than the DD group.
SEM images showed that WT_AgNPs presented different degrees of aggregation and distribution patterns. The
dentine flexural strength was significantly increased in all WT_AgNPs. The application of WT_AgNPs demonstrated
remineralising and strengthening potential on demineralised dentine.},
organization = {Spanish Ministry of Economy and
Competitiveness [grant number PID2020-116660GB-I00, RNM-408-UGR20]},
organization = {European Regional Development Fund (ERDF) - Next
Generation/EU program},
publisher = {Elsevier},
keywords = {Silver nanoparticles},
keywords = {Plant extract},
keywords = {Green chemistry technology},
title = {Green synthesis of chitosan- and fluoride-functionalized silver nanoparticles using Camellia sinensis: Characterization and dental applications},
doi = {10.1016/j.ijbiomac.2024.131676},
author = {Cifuentes Jiménez, Carolina Cecilia and Bolaños Carmona, María Victoria and Enrich Essvein, Tattiana and Rodríguez Navarro, Alejandro and González López, Santiago and Yamauti, Monica and Álvarez Lloret, Pedro},
}