@misc{10481/92697,
year = {2024},
month = {2},
url = {https://hdl.handle.net/10481/92697},
abstract = {Surface-adhered bacteria on implants represent a major challenge
for antibiotic treatment. We introduce hydrogel-coated surfaces
loaded with tailored Pd-nanosheets which catalyze the release of
antibiotics from inactive prodrugs. Masked and antibiotically
inactive fluoroquinolone analogs were efficiently activated at the
surface and prevented the formation of Staphylococcus aureus
biofilms.},
organization = {Doctoral fellowship of the Foundation
of German Business},
organization = {Merck
Future Insight Prize 2020},
organization = {EC (H2020-MSCA–IF–2018-841990)},
organization = {EPSRC (EP/S010289/1)},
organization = {EU H2020 (grant agreement no 823717 – ESTEEM3)},
publisher = {Royal Society of Chemistry},
title = {A Pd-labile fluoroquinolone prodrug efficiently prevents biofilm formation on coated surfaces},
doi = {10.1039/d4ob00014e},
author = {Braun, Josef and Ortega Liébana, M. Carmen and Unciti-Broceta, Asier and Sieber, Stephan A.},
}