@misc{10481/92451,
year = {2024},
month = {4},
url = {https://hdl.handle.net/10481/92451},
abstract = {Water recycling and reuse are cornerstones of water management, which can be compromised
by the presence of pollutants. Among these, pharmaceuticals can overcome standard water
treatments and require sophisticated approaches to remove them. Sorption is an economically viable
alternative limited by the need for sorbents with a sorption coefficient (Kd) higher than 500 L/kg.
The cross-linking of dextrin (Dx) with divinyl sulfone (DVS) in the presence of 1 mmol or 5 mmol of
ibuprofen (IBU) yields the insoluble polymers pDx1 and pDx5 with improved affinity for IBU and
high selectivity towards erythromycin (ERY) and ERY Kd higher than 4 × 103 L/kg, when tested
against a cocktail of six drugs. Characterization of the polymers shows that both pDx1 and pDx5
have similar properties, fast sorption kinetics, and ERY Kd of 13.3 × 103 for pDx1 and 6.4 × 103
for pDx5, representing 26.6 and 12.0 times the 500 L/kg threshold. The fact that new affinities and
improvements in Kd can be achieved by cross-linking Dx in the presence of other molecules that promote
pre-organization expands the applications of DVS cross-linked polysaccharides as sustainable,
scalable, and environmentally friendly sorbents with a potential application in wastewater treatment
plants (WTPs).},
organization = {Junta de Andalucía through the research project B-FQM-316-UGR20 funded by the Programa Operativo FEDER Andalucía},
publisher = {MDPI},
keywords = {Cross-linking},
keywords = {Dextrin},
keywords = {Divinyl sulfone},
title = {Removal of Erythromycin fromWater by Ibuprofen-Driven Pre-Organized Divinyl Sulfone Cross-Linked Dextrin},
doi = {10.3390/polym16081090},
author = {Ortega Muñoz, Mariano and Alvarado, Sarah and Megía Fernández, Alicia and Hernández Mateo, Fernando and López Jaramillo, Francisco Javier and Santoyo González, Francisco},
}