@misc{10481/91852,
year = {2024},
month = {4},
url = {https://hdl.handle.net/10481/91852},
abstract = {Metal–organic frameworks (MOFs) possess a variety of interesting features related to their composition and structure that make them excellent candidates to be used in agriculture. However, few studies have reported their use as delivery agents of agrochemicals. In this work, the natural polyphenol chlorogenic acid (CGA) was entrapped via simple impregnation in the titanium aminoterephthalate MOF, MIL-125-NH2. A combination of experimental and computational techniques was used to understand and quantify the encapsulated CGA in MIL-125-NH2. Subsequently, CGA delivery studies were carried out in water at different pHs, showing a fast release of CGA during the first 2 h (17.3 ± 0.3% at pH = 6.5). In vivo studies were also performed against larvae of mealworm (Tenebrio molitor), evidencing the long-lasting insecticidal activity of CGA@MIL-125-NH2. This report demonstrates the potential of MOFs in the efficient release of agrochemicals, and paves the way to their study against in vivo models.},
organization = {Project
MOFseidon PID2019-104228RB-I00, AgroMOFs TED2021-
132440B-I00 and MOFCycle CNS2022-135779 funded by
MCIN/AEI/10.13039/501100011033},
organization = {B-FQM-394, and ProyExcel_
00105 funded by Junta de Andalucıía},
organization = {Grant (RYC2021-032522-I) funded by MCIN/AEI/10.13039/
501100011033},
organization = {FSE invierte en tu futuro},
organization = {Funding for
open access charge: University of Granada/CBUA},
publisher = {Royal Society of Chemistry},
title = {Long-lasting insecticidal activity in plants driven by chlorogenic acid-loaded metal–organic frameworks},
doi = {10.1039/D3TB02493H},
author = {Rincón, Irene and Contreras Morales, María del Carmen and Sierra Serrano, Beatriz and Salles, Fabrice and Rodríguez Diéguez, Antonio and Rojas Macías, Sara and Horcajada, Patricia},
}