@misc{10481/91585,
year = {2023},
month = {12},
url = {https://hdl.handle.net/10481/91585},
abstract = {Purpose: To compare the strength of associations between different indices
of cardiorespiratory fitness (CRF) and brain health outcomes in children with
overweight/obesity.
Methods: Participants were 100 children aged 8–11 years. CRF was assessed
using treadmill exercise test (peak oxygen uptake [V̇O2peak], treadmill time, and
V̇O2 at ventilatory threshold) and 20-metre
shuttle run test (20mSRT, laps, running
speed, estimated V̇O2peak using the equations by Léger et al., Mahar et al.,
and Matsuzaka et al.). Intelligence, executive functions, and academic performance
were assessed using validated methods. Total gray matter and hippocampal
volumes were assessed using structural MRI.
Results: V̇O2peak/body mass (β = 0.18, 95% CI = 0.01–0.35) and treadmill time
(β = 0.18–0.21, 95% CI = 0.01–0.39) were positively associated with gray matter
volume. 20mSRT laps were positively associated with executive functions (β = 0.255, 95% CI = 0.089–0.421) and academic performance (β = 0.199–0.255, 95%
CI = 0.006–0.421), and the running speed was positively associated with executive
functions (β = 0.203, 95% CI = 0.039–0.367). Estimated V̇O2peak/Léger et al. was positively
associated with intelligence, executive functions, academic performance,
and gray matter volume (β = 0.205–0.282, 95% CI = 0.013–0.500). Estimated
V̇O2peak/Mahar et al. and V̇O2peak/Matsuzaka et al. (speed) were positively associated with
executive functions (β = 0.204–0.256, 95% CI = 0.031–0.436).
Conclusion: Although V̇O2peak is considered the gold standard indicator of
CRF in children, peak performance (laps or running speed) and estimated
V̇O2peak/Léger et al. derived from 20mSRT had stronger and more consistent associations
with brain health outcomes than other indices of CRF in children with
overweight/obesity.},
organization = {Grants from the Spanish Ministry of Economy and Competitiveness (DEP2013-47540, DEP2016-79512-R, and DEP2017-91544-EXP)},
organization = {European Regional Development Fund (ERDF)},
organization = {European Commission (667302)},
organization = {Alicia
Koplowitz Foundation},
organization = {Andalusian Operational Programme
supported with ERDF (FEDER in Spanish, B-CTS-355-UGR18)},
organization = {University
of Granada, Plan Propio de Investigación, Visiting Scholar
grants and Excellence actions: Units of Excellence},
organization = {Unit of Excellence on Exercise, Nutrition and Health
(UCEENS)},
organization = {Junta de Andalucía, Consejería
de Conocimiento, Investigación y Universidades and the
ERDF (SOMM17/6107/UGR)},
organization = {Spanish Ministry of Science and Innovation (RyC2019-027287-
1)},
organization = {Grant from ANID/BECAS Chile/72180543},
organization = {Margarita Salas
grant from the Spanish Ministry Universities},
organization = {Juho Vainio Foundation},
organization = {NIH grant #: U01 TR002004
(REACH project)},
publisher = {John Wiley & Sons},
keywords = {Brain},
keywords = {Child},
keywords = {Cognition},
title = {Which indices of cardiorespiratory fitness are more strongly associated with brain health in children with overweight/obesity?},
doi = {10.1111/sms.14549},
author = {Haapala, Eero A. and Lubans, David R. and Jaakkola, Timo and Barker, Alan R. and Plaza Florido, Abel Adrián and Gracia Marco, Luis Andrés and Solís Urra, Patricio and Cadenas Sánchez, Cristina and Esteban Cornejo, Irene and Ortega Porcel, Francisco Bartolomé},
}