@misc{10481/90971, year = {2015}, month = {10}, url = {https://hdl.handle.net/10481/90971}, abstract = {Cross-sectional study comparing seminal human immunodeficiency virus type 1 (HIV-1) shedding in patients receiving boosted protease inhibitor monotherapy (mtPI/rtv) (n = 66) versus triple therapy (TT) (n = 61). Seminal HIV-1 shedding rates in patients with undetectable plasma HIV-RNA were 16.0% on mtPI/rtv compared with 28.6% on TT (p 0.173). Aviraemic status and time on viral suppression were independently associated with lack of seminal HIV-1 shedding. During TT, non PI/rtv-based regimens were associated with a better control of HIV infection in semen despite similar time on viral suppression. The use of mtPI/rtv in well-controlled patients is not associated with increased seminal HIV excretion compared with TT.}, organization = {Junta de Andalucía PI-0168-2012}, publisher = {Elsevier}, keywords = {Human immunodeficiency virus 1 infection}, keywords = {Human immunodeficiency virus 1 treatment}, keywords = {Male genital tract}, keywords = {Protease inhibitor monotherapy}, keywords = {Triple therapy}, title = {Protease inhibitor monotherapy is effective in controlling human immunodeficiency virus 1 shedding in the male genital tract}, doi = {10.1016/j.cmi.2015.09.028}, author = {Torres-Cornejo, A and BenMarzouk-Hidalgo, OJ and Viciana, P and Sánchez, B and López Ruz, Miguel Ángel and López Cortes, LF and Gutiérrez Valencia, A}, }