@misc{10481/90335,
year = {2023},
url = {https://hdl.handle.net/10481/90335},
abstract = {This article, the second in a two-part series, continues the discussion on the nature of the relationship
between the level of sweet taste suppression and eating behaviour, but in animal rather
human subjects. In particular, the aim was to review the scientific literature on the impact that
bioactive compounds that decrease oral sweet sensations have on intake, preference and physiological
status in preclinical studies. This review was registered in the International Prospective
Register of Systematic Reviews and conducted according to the Preferred Reporting Items for Systematic
Reviews and Meta-Analyses (PRISMA) and the Scottish Intercollegiate Guidelines Network and
covered original papers included in Web of Science, PubMed, Scopus, Food Science Source and
Food Science and technology abstracts. We identified 28 peer-reviewed English-language studies
that fit the topic and met the inclusion criteria. We identified three plant species, Gymnema sylvestre,
Hovenia dulcis, and Ziziphus jujuba, that possess acute sweetness-inhibitory properties.
When administered orally, these plants reduced neural responses to sweet stimuli and decreased
consumption. However, studies on the longer-term effects of antisweet activity remain to be
conducted. Translating the valuable insights into the mechanisms underlying the relationship
between sweet taste impairment and eating behaviour into practical clinical applications are
discussed.},
organization = {Grant PID2021-129042OA-I00 funded by MCIN/AEI/10.13039/501100011033 and “ERDF A way of making Europe”},
organization = {FPU Fellowship under Grant FPU20/02400 (Ministry of Universities, Spain)},
organization = {Funding
for open access charge: Universidad de Granada/CBUA},
publisher = {Elsevier},
keywords = {Anti-sweet},
keywords = {Diet-induced obesity},
keywords = {Gymnema sylvestre},
title = {Suppression of sweet taste-related responses by plant-derived bioactive compounds and eating. Part II: A systematic review in animals},
doi = {10.1016/j.heliyon.2023.e20511},
author = {Rayo Morales, Raquel and Segura Carretero, Antonio and Borras Linares, María Isabel and García Burgos, David},
}