@misc{10481/88964,
year = {2022},
month = {11},
url = {https://hdl.handle.net/10481/88964},
abstract = {In magnetic nanoparticle hyperthermia, the magnetic nanoparticles (MNPs) start oscillations when they are exposed to an alternating magnetic field, which may generate ultrasound waves. These resulting oscillations of nanoparticles can lead to the movement of drug carrier liposomes. In this study, a multiphysics coupling model of magnetic nanoparticle behavior in an alternating magnetic field was developed, implementing solid mechanics compliance parameters and piezomagnetic coupling matrices. A detailed sensitivity study was conducted to examine the effects of size and elastic modulus of MNPs, distribution and distance between two MNPs, elasticity and viscosity of the glycerol medium and mesh element sizes on the output displacement signals of MNPs. The results indicated that magnetic nanoparticles undergo some displacements when they are exposed to an alternating magnetic field. These oscillations may generate ultrasound waves, though the amount of displacement for each nanoparticle is negligibly small. It is expected that aggregated nanoparticles result in much higher oscillations.},
organization = {Department of Statistics and Operations Research, University of Granada, Granada, Spain},
organization = {bMNat Scientific Unit of Excellence, University of Granada, Spain},
organization = {Instituto de Investigación Biosanitaria, ibs.GRANADA, Spain},
organization = {Department of Structural Mechanics, University of Granada, Spain},
organization = {Department of Civil Engineering, University of Granada, Spain},
publisher = {Taylor & Francis},
keywords = {Magnetic Nanoparticle Hyperthermia},
keywords = {Alternating magnetic field},
keywords = {Drug delivery},
keywords = {Multiphysics},
title = {Numerical modelling of magnetic nanoparticle behavior in an alternating magnetic field based on multiphysics coupling},
doi = {10.1080/15376494.2022.2136805},
author = {Ashofteh, Alireza and Marqués, Rafael and Callejas Zafra, Antonio Manuel and Muñoz Beltrán, Rafael and Melchor Rodríguez, Juan Manuel},
}