@misc{10481/87284,
year = {2010},
month = {11},
url = {https://hdl.handle.net/10481/87284},
abstract = {Consumption of high-protein (HP) diets is postulated to exert a negative influence on bone and renal health. However, no conclusive
evidence has been presented related to this issue or to the potential protective action of resistance training on HP-induced systemic effects. We examined the effects of HP diet consumption on food intake, body-weight gain, body composition, and renal, bone and metabolic
parameters of rats performing resistance training. A total of ninety-six adult male Wistar rats were randomly distributed in twelve experimental groups (n 8): normal-protein (10 %) or HP (45 %) diets, with or without resistance training, killed for experimental periods of 1, 2 or 3 months. Diets were based on a commercial whey protein hydrolysate. Consumption of HP diets and resistance training significantly affected food intake, body weight and body composition, as well as the plasma levels of total cholesterol, HDL-cholesterol and TAG. The buffering action of resistance training on such diet-induced alterations was especially evident in the levels of plasma TAG. Consumption of HP diets led to a considerable increase in kidney weight, urinary volume and acidity, as well as in the urinary excretion of Ca, with a parallel reduction in the urinary excretion of citrate (P,0·05). No apparent deleterious effect on bone mineral content was found.
In conclusion, consumption of HP diets caused alterations in renal health status and some metabolic parameters, but did not seem to
affect bone status. Resistance training had a protective action against alterations of renal health status and some metabolic parameters
such as plasma TAG.},
organization = {The authors gratefully acknowledge Encarnacio´n Rebollo
and all the members from the Department of Physiology
for their collaboration, especially to the persons involved
in the fieldwork for their efforts and great enthusiasm.
The present study was financially supported by the project
2007/20SVC of the Andalusian Center of Sport Medicine
and grants from the Spanish Ministry of Education
(EX-2008-0641) and Ministry of Science and Innovation
(BES-2009-013442).},
publisher = {Cambridge University Press},
title = {Effects of high-whey-protein intake and resistance training on renal, bone and metabolic parameters in rats},
doi = {10.1017/S0007114510004393},
author = {Aparicio García-Molina, Virginia and Nebot Valenzuela, Elena and Porres Foulquie, Jesús María and Ortega Porcel, Francisco Bartolomé and Heredia Jiménez, José María and López-Jurado Romero De La Cruz, María and Aranda Ramírez, Pilar},
}