@misc{10481/85342,
year = {2023},
month = {10},
url = {https://hdl.handle.net/10481/85342},
abstract = {The flavivirus West Nile virus (WNV) naturally circulates between mosquitoes and birds, potentially affecting humans and horses. Different species of mosquitoes play a role as vectors of WNV, with those of the Culex pipiens complex being particularly crucial for its circulation. Different biotic and abiotic factors determine the capacity of mosquitoes for pathogen transmission, with the mosquito gut microbiota being recognized as an important one. Here, we review the published studies on the interactions between the microbiota of the Culex pipiens complex and WNV infections in mosquitoes. Most articles published so far studied the interactions between bacteria of the genus Wolbachia and WNV infections, obtaining variable results regarding the directionality of this relationship. In contrast, only a few studies investigate the role of the whole microbiome or other bacterial taxa in WNV infections. These studies suggest that bacteria of the genera Serratia and Enterobacter may enhance WNV development. Thus, due to the relevance of WNV in human and animal health and the important role of mosquitoes ofthe Cx. pipiens complex in its transmission, more research is needed to unravel the role of mosquito microbiota and those factors affecting this microbiota on pathogen epidemiology. In this respect, we finally propose future lines of research lines on this topic.},
organization = {This research was funded by the MCIN/AEI/10.13039/501100011033 (grant number PID2020-118205GB-I00) and the Junta de Andalucía, Consejería de Universidad, Investigación e Innovación (grant number P21_00049). The current contracts of M. Garrigós and J.V. are financed by the Spanish Ministry of Science and Innovation (grant numbers PRE2021-098544 and FJC2021-048057-I, respectively). In addition, M. Garrido and J.V. were financed by the Spanish Ministry of Universities (Margarita Salas and María Zambrano programs, respectively). The APC was funded by University of Granada.},
keywords = {Mosquito},
keywords = {vector competence},
keywords = {Wolbachia},
keywords = {Flavivirus},
keywords = {mosquito-borne pathogens},
keywords = {mosquito microbiota},
title = {Interactions between West Nile Virus and the Microbiota of Culex pipiens Vectors: A Literature Review},
doi = {10.3390/pathogens12111287},
author = {Garrigós, Marta and Garrido Escudero, Mario and Panisse, Guillermo and Veiga, Jesús and Martínez-de la Puente, Josué},
}