@misc{10481/84805, year = {2021}, month = {10}, url = {https://hdl.handle.net/10481/84805}, abstract = {Since interleukin-6 (IL-6) is a pivotal proinflammatory cytokine implicated in the pathogenesis of giant cell arteritis (GCA), we aimed to determine the potential association of the functional IL6 -174 G/C polymorphism with GCA as well as if the single base change variation at the promoter region in the human IL-6 gene may account for differences in the clinical spectrum of GCA between cranial and extracranial large-vessel vasculitis (LVV)-GCA.}, organization = {Instituto de Salud Carlos III CM20/00006}, organization = {European Union (EU)}, organization = {Instituto de Salud Carlos III Spanish Government}, organization = {Marie Curie Actions European Union (EU) RD16/0012/0014 PI17/00409}, organization = {Research Executive Agency (REA) of the European Union 734899-Olive-Net}, organization = {Instituto de Salud Carlos III Spanish Government}, organization = {European Social Fund (ESF) CP16/00033}, publisher = {Springer Nature}, keywords = {Giant cell arteritis}, keywords = {Large-vessel vasculitis}, keywords = {IL6 -174 G/C (rs1800795)}, keywords = {Polymorphism}, title = {Cranial and extracranial giant cell arteritis do not exhibit differences in the IL6 -174 G/C gene polymorphism}, doi = {10.1186/s13075-021-02659-9}, author = {Genre, F. and Ortego Centeno, Norberto}, }