@misc{10481/84579,
year = {2023},
month = {7},
url = {https://hdl.handle.net/10481/84579},
abstract = {Avocado peel and seed are the main by-products of avocado processing and are considered
as promising sources of phenolic compounds with biological activities. Thus, this research
focuses on the establishment, for the first time, of ultrasound-assisted extraction of flavan-3-ols with
high antioxidant activity from avocado peel and seed using a sonotrode. Indeed, 2 Box–Behnken
designs were performed for 15 experiments, with each design having three independent factors (ratio
ethanol/water (v/v), time (min) and amplitude (%)). In both models, the responses included total
procyanidins (flavan-3-ols) measured via HPLC-FLD and antioxidant activity measured via DPPH,
ABTS and FRAP. The results showed that applying the sonotrode extraction method could increase
flavan-3-ols recovery by 54% and antioxidant activity by 62–76% compared to ultrasound bath technology.
Therefore, this technology was demonstrated to be a non-thermal, low time-consuming and
scalable method that allowed the recovery of flavan-3-ols from avocado by-products that could be
used as functional ingredients},
organization = {SHEALTHY project, which receives funding from the
European Union’s Horizon 2020 research and innovation program under grant number 817936},
organization = {The
project RTI2018-099835-A-I00 financed by MCIN/AEI/10.13039/501100011033/FEDER “Una manera
Antioxidants 2023, 12, 1409 12 of 13
de hacer Europa”},
organization = {Project Proyectos I + D + i del Programa Operativo FEDER 2020 cod.
B-AGR-506-UGR20},
publisher = {MDPI},
keywords = {Avocado seed},
keywords = {Avocado peel},
keywords = {Flavan-3-ols},
keywords = {Sonotrode},
keywords = {Procyanidins},
title = {Response Surface Methodology for the Optimization of Flavan-3-ols Extraction from Avocado By-Products via Sonotrode Ultrasound-Assisted Extraction},
doi = {10.3390/ antiox12071409},
author = {Razola Díaz, María del Carmen and Verardo, Vito and Guerra Hernández, Eduardo Jesús and García Villanova Ruiz, Belén and Gómez Caravaca, Ana María},
}