@misc{10481/83898, year = {2023}, month = {5}, url = {https://hdl.handle.net/10481/83898}, abstract = {Background Unhealthy dietary patterns (DP) have been frequently linked to avoidable ill-health, mediated in part through higher body mass index. However it is unclear how these patterns relate to specific components of body composition or fat distribution, and whether this may explain reported gender differences in the relationship between diet and health. Methods Data from 101,046 UK Biobank participants with baseline bioimpedance analysis and anthropometric measures and dietary information on two or more occasions were used, of which 21,387 participants had repeated measures at follow up. Multivariable linear regressions estimated the associations between DP adherence (categorised in quintiles Q1–Q5) and body composition measures adjusted for a range of demographic and lifestyle confounders. Results After 8.1 years of follow-up, individuals with high adherence (Q5) to the DP showed significantly positive changes in fat mass (mean, 95 % CI): 1.26 (1.12–1.39) kg in men, 1.11 (0.88–1.35) kg in women vs low adherence (Q1) − 0.09 (− 0.28 to 0.10) kg in men and − 0.26 (− 0.42 to − 0.11) kg in women; as well as in waist circumference (Q5): 0.93 (0.63–1.22) cm in men and 1.94 (1.63, 2.25) cm in women vs Q1 − 1.06 (− 1.34 to − 0.78) cm in men and 0.27 (− 0.02 to 0.57) cm in women. Conclusion Adherence to an unhealthy DP is positively associated with increased adiposity, especially in the abdominal region, which may help explain the observed associations with adverse health outcomes.}, organization = {Ramon y Cajal Fellowship RYC2020-028818-I (Ministry of Science and Innovation, Spain)}, organization = {Oxford NIHR Biomedical Research Centre}, organization = {NIHR Oxford and Thames Valley Applied Research Collaboration and NIHR Biomedical Research Centre}, organization = {Cancer Research UK Population Research Fellowship (C60192/A28516)}, organization = {World Cancer Research Fund (WCRF UK),}, organization = {Word Cancer Research Fund International Grant Programme (2019/1953)}, organization = {CTSU (Clinical Trial Service Unit)}, organization = {Council and the British Heart Foundation (CH/ 1996001/9454)}, organization = {UK Biobank was established by the Wellcome Trust, Medical Research Council}, organization = {Department of Health, Scottish government,}, organization = {Northwest Regional Development Agency}, organization = {Welsh assembly government and the British Heart Foundation}, organization = {Department of Health and Social Care}, publisher = {Elsevier}, keywords = {Reduced rank regression}, keywords = {Fat mass}, keywords = {Skeletal muscle mass}, keywords = {BMI}, keywords = {Waist circumference}, keywords = {Cohort study}, title = {Dietary pattern adherence in association with changes in body composition and adiposity measurements in the UK Biobank study}, doi = {10.1016/j.orcp.2023.05.008}, author = {Sweetman, Anna K. and Piernas Sánchez, Carmen María}, }