@misc{10481/81775,
year = {2023},
month = {4},
url = {https://hdl.handle.net/10481/81775},
abstract = {Background Alzheimer’s disease (AD) is a neurodegenerative disease without known cure. However, early medical
treatment can help control its progression and postpone intellectual decay. Since AD is preceded by a period of cognitive
deterioration, the effective assessment of cognitive capabilities is crucial to develop reliable screening procedures.
For this purpose, cognitive tests are extensively used to evaluate cognitive areas such as language, attention, or
memory.
Methods In this work, we analyzed the potential of a visual dynamics evaluation, the rapid serial visual presentation
task (RSVP), for the detection of cognitive impairment in AD. We compared this evaluation with two of the most
extended brief cognitive tests applied in Spain: the Clock-drawing test (CDT) and the Phototest. For this purpose, we
assessed a group of patients (mild AD and mild cognitive impairment) and controls, and we evaluated the ability of
the three tests for the discrimination of the two groups.
Results The preliminary results obtained suggest the RSVP performance is statistically higher for the controls than for
the patients (p-value = 0.013). Furthermore, we obtained promising classification results for this test (mean accuracy
of 0.91 with 95% confidence interval 0.72, 0.97).
Conclusions Since the RSVP is a computerized, auto-scored, and potentially self-administered brief test, it could
contribute to speeding-up cognitive impairment screening and to reducing the associated costs. Furthermore, this
evaluation could be combined with other tests to augment the efficiency of cognitive impairment screening protocols
and to potentially monitor patients under medical treatment.},
organization = {FEDER/Junta de Andalucía-Council for Economic
Transformation, Industry, Knowledge and Universities/ grant (B-TIC-352-
UGR20); grant PID2021-128529OA-I00, MCIN / AEI / 10.13039 / 501100011033},
organization = {ERDF A way of making Europe; grant PROYEXCEL_00084, Projects for
Excellence Research,},
organization = {Council for Economic Transformation,},
organization = {Industry, Knowledge
and Universities, Junta de Andalucía 2021},
organization = {Circuits And Systems
for Information Processing (CASIP) research group, TIC-117 (PAIDI Junta de
Andalucia)},
organization = {PGC2018-098813-B-C31 and PGC2018-098813-B-C32 (Spanish
Ministry of Science, Innovation and Universities)},
publisher = {Springer Nature},
keywords = {Alzheimer’s disease},
keywords = {Screening},
keywords = {Visual dynamics},
keywords = {Cognitive test},
title = {Evaluating the feasibility of cognitive impairment detection in Alzheimer’s disease screening using a computerized visual dynamic test},
doi = {10.1186/s12984-023-01155-2},
author = {Pérez Valero, Eduardo and Morillas Gutiérrez, Christian Agustín and López Gordo, Miguel Ángel and López Alcalde, Samuel},
}