@misc{10481/81653,
year = {2023},
url = {https://hdl.handle.net/10481/81653},
abstract = {The background of this study is to examine the associations of individual and combined early morning patterns (i.e., active
commuting to school, physical activity before school, having breakfast and good sleep) with white matter microstructure
(WMM) and, whether the associated white mater microstructure outcomes were related to mental health outcomes in children
with overweight or obesity. 103 children with overweight or obesity (10.0 ± 1.1 years old, 42 girls) from the ActiveBrains
project participated in this cross-sectional study. Early morning patterns and mental health indicators (i.e., self-esteem,
optimism, positive and negative affect, stress, depression and anxiety) were self-reported by the children using validated
questionnaires. WMM was assessed by magnetic resonance imaging using diffusion tensor imaging. When examined independently,
early morning patterns were not related with WMM (all P > 0.05). However, the combination of early morning
patterns was related with WMM (P < 0.05). Specifically, physically active early morning patterns (i.e., active commuting
to school and physical activity before school) were associated with global fractional anisotropy (FA) (β = 0.298, P = 0.013)
and global radial diffusivity (RD) (β = − 0.272, P = 0.021), as well as with tract-specific FA (β = 0.314, P = 0.004) and
RD (β = − 0.234, P = 0.032) in the superior longitudinal fasciculus (SLF). Furthermore, combined physically active early
morning pattern-associated global (i.e., FA and RD) and tract-specific (i.e., FA and RD in the SLF) WMM indicators were
positively associated with happiness (β absolute value range from 0.252 to 0.298, all P < 0.05). A combination of physically
active early morning patterns may positively relate to white matter microstructure in children with overweight or obesity,
and, in turn, happiness.},
organization = {Universidad de Granada/CBUA},
organization = {Spanish Government	DEP2013-47540
BES-2014-068829
DEP2016-79512-R
PSI2012-3929},
organization = {Alicia Koplowitz Foundation},
organization = {Ministry of Science and Innovation, Spain (MICINN)
Spanish Government	RYC-2011-09011
RYC2019-027287-I},
organization = {University of Granada},
organization = {Junta de Andalucia, Consejeria de Conocimiento, Investigacion y Universidades and European Regional Development Fund (ERDF)	SOMM17/6107/UGR},
organization = {EXERNET Research Network on Exercise and Health in Special Populations	DEP2005-00046/ACTI},
organization = {SAMID III network},
organization = {RETICS	PN I + D + I 2017-2021},
organization = {ISCIII-Sub -Directorate General for Research Assessment and Promotion},
organization = {European Commission	SOMM17/6107/UGR
RD16/0022},
organization = {Universidad de Granada/CBUA},
publisher = {Springer Nature},
keywords = {Neurodevelopment},
keywords = {Psychological health},
keywords = {White matter integrity},
keywords = {Physical Activity},
keywords = {Diet},
keywords = {Sleep},
keywords = {Childhood},
keywords = {Obesity},
title = {Early morning physical activity is associated with healthier white matter microstructure and happier children: the ActiveBrains project},
doi = {10.1007/s00787-023-02197-6},
author = {Esteban Cornejo, Irene and Lara Jimenez, Inmaculada and Verdejo Román, Juan and Erickson, Kirk I. and Ortega Porcel, Francisco Bartolomé},
}