@misc{10481/80417,
year = {2022},
month = {12},
url = {https://hdl.handle.net/10481/80417},
abstract = {The definition of metabolic syndrome (MetS) based on dichotomous cut-off points is
efficient in the adult population. However, to date, there is no international consensus on how to
define MetS in the pediatric population. For that reason, a continuous MetS score (cMetS) has been
proposed for the pediatric population. However, despite multiple attempts, cMetS has not been fully
validated as there is no agreement about the most accurate score to calculate it. The purpose of the
present study was to compare the validity of different scores (three siMS scores, z-score, principal
components analysis (PCA), the sum of PCA, and confirmatory factor analysis) to calculate cMetS and
determine MetS in Spanish adolescents. There were 981 subjects, ranging 11–16 years old, recruited
for this cross-sectional study. Seven different approaches to pediatric cMetS scores were calculated.
All cMetS scores calculated strongly correlated with each other, especially siMS scores. The area
under the curve obtained from receiving operating characteristic curves was particularly elevated for
z-scores 0.81 (95% CI: 0.784–0.838), showing a specificity of 64.4%. Our study shows that cMetS based
on z-scores is accurate and efficient to be used for research instead of the dichotomized definition of
MetS in adolescents; and cMetS based on siMS scores is useful for clinical practice.},
organization = {Andalusia 2014–2020 European Regional Development
Fund (ERDF) Operative Program, grant number B-AGR-287-UGR18},
publisher = {MDPI},
keywords = {Metabolic syndrome},
keywords = {Continuous metabolic syndrome},
keywords = {Adolescents},
keywords = {Determination},
keywords = {Criteria},
title = {cMetS Based on Z-Scores as an Accurate and Efficient Scoring System to Determine Metabolic Syndrome in Spanish Adolescents},
doi = {10.3390/jpm13010010},
author = {Fernández Aparicio, Ángel and Schmidt Río Valle, Jacqueline and Montero Alonso, Miguel Ángel and González Jiménez, Emilio},
}