@misc{10481/79062,
year = {2022},
month = {11},
url = {https://hdl.handle.net/10481/79062},
abstract = {Metal–organic frameworks (MOFs) can be used as reservoirs of metal ions with relevant
antibacterial effects. Here, two novel Zn-based MOFs with the formulas [Zn4( 4-O)( -FA)L2]
(GR-MOF-8) and [Zn4( 4-O)L2(H2O)] (GR-MOF-9) (H3L: 5-((4-carboxyphenyl)ethynyl) in isophthalic
acid and FA (formate anion) were solvothermally synthetized and fully characterized. The antibacterial
activity of GR-MOF-8 and 9 was investigated against Staphylococcus aureus (SA) and Escherichia
Coli (EC) by the agar diffusion method. Both bacteria are among the most relevant human and
animal pathogens, causing a wide variety of infections, and are often related with the development
of antimicrobial resistances. While both Zn-based materials exhibited antibacterial activity against
both strains, GR-MOF-8 showed the highest inhibitory action, likely due to a more progressive Zn
release under the tested experimental conditions. This is particularly evidenced in the inhibition of
SA, with an increasing effect of GR-MOF-8 with time, which is of great significance to ensure the
disappearance of the microorganism.},
organization = {MCIN/AEI by the European Union NextGenerationEU/PRTR)	PCI2020-111998	
MCIN/AEI	PID2019-104228RB-100	
PGC2018-102052-B-C21	
JC2019-038894-I},
organization = {Junta de Andalucia	B-FQM-734-UGR20	
B-FQM-478-UGR20	
FQM-394},
organization = {Comunidad de Madrid	RED2018-102471-T},
organization = {European Regional Development Fund-FEDER 2014-2020-OE REACT-UE 1},
organization = {SKA South Africa	897678},
organization = {Madrid Community	2018-T2/IND-11407	
2017-T2/IND-5149},
organization = {European Union NextGenerationEU/PRTR},
publisher = {MDPI},
keywords = {Metal-organic frameworks},
keywords = {Zinc},
keywords = {Antibacterial activity},
title = {Antibacterial Activity of Two Zn-MOFs Containing a Tricarboxylate Linker},
doi = {10.3390/nano12234139},
author = {Rojas Macías, Sara and García García, Amalia and Rosales, María and Montes Andrés, Helena and Rodríguez Diéguez, Antonio},
}