@misc{10481/78411,
year = {2022},
month = {11},
url = {https://hdl.handle.net/10481/78411},
abstract = {Hypoxic exposure is safely associated with exercise for many pathological
conditions, providing additional effects on health outcomes. COVID-19 is a new
disease, so the physiological repercussions caused by exercise in affected patients
and the safety of exposure to hypoxia in these conditions are still unknown. Due to
the effects of the disease on the respiratory system and following the sequence of
AEROBICOVID research work, this study aimed to evaluate the effectiveness,
tolerance and acute safety of 24 bicycle training sessions performed under
intermittent hypoxic conditions through analysis of peripheral oxyhemoglobin
saturation (SpO2), heart rate (HR), rate of perceived exertion (RPE), blood lactate
concentration ([La−]) and symptoms of acute mountain sickness in patients
recovered from COVID-19. Participants were allocated to three training groups:
the normoxia group (GN) remained in normoxia (inspired fraction of O2 (FiO2) of
~20.9%, a city with 526m altitude) for the entire session; the recovery hypoxia
group (GHR) was exposed to hypoxia (FiO2 ~13.5%, corresponding to 3,000m
altitude) all the time except during the effort; the hypoxia group (GH) trained in
hypoxia (FiO2 ~13.5%) throughout the session. The altitude simulation effectively
reduced SpO2 mean with significant differences between groups GN, GHR, andGH,
being 96.9(1.6), 95.1(3.1), and 87.7(6.5), respectively. Additionally, the proposed
exercise and hypoxic stimuluswaswell-tolerated, since 93% of participants showed
no or moderate acutemountain sickness symptoms; maintained nearly 80% of sets
at target heart rate; andmost frequently reporting session intensity as an RPE of “3” (moderate). The internal load calculation, analyzed through training impulse
(TRIMP), calculated using HR [TRIMPHR = HR * training volume (min)] and RPE
[TRIMPRPE = RPE * training volume (min)], showed no significant difference
between groups. The current strategy effectively promoted the altitude
simulation and monitoring variables, being well-tolerated and safely acute
exposure, as the low Lake Louise scores and the stable HR, SpO2, and RPE
values showed during the sessions.},
organization = {'USP Vida' Project from USP	3518/2020},
organization = {Integrated Research Projects in Strategic Areas from USP	PIPAE 2021.1.10424.1.9},
organization = {PDU EFISAL - Universidad de la Republica	003051-000603-16},
publisher = {Frontiers},
keywords = {Coronavirus infections},
keywords = {Exercise},
keywords = {Oxygen},
keywords = {Physiologic monitoring},
keywords = {Altitude},
keywords = {Convalescence},
title = {Effectiveness, implementation, and monitoring variables of intermittent hypoxic bicycle training in patients recovered from COVID-19: The AEROBICOVID study},
doi = {10.3389/fphys.2022.977519},
author = {Peinado Costa, Gabriel and Camacho Cardeñosa, Alba},
}