@misc{10481/78066,
year = {2022},
month = {10},
url = {https://hdl.handle.net/10481/78066},
abstract = {The use of phytogenic extracts is considered a sustainable strategy for the prevention
of fish diseases, including Alliaceae as a potential option due to their variety of bioactive compounds.
In this study, we analyzed the antibacterial and antiparasitic potential of propyl-propanethiosulfinate
(PTS) and propyl-propane-thiosulfonate (PTSO) from onions. The in vitro activity
against Pseudomonas anguilliseptica, Tenacibaculum maritimum, and Photobacterium damselae of both
compounds was tested. In addition, the viability of Sparicotyle chrysophrii larvae was evaluated.
Moreover, a diet that consisted of a blend of PTS/PTSO (ALLIUM) was used. A total of 90 gilthead
sea bream juveniles were tested against P. damselae subsp. Piscicida after 12 weeks of dietary administration.
Furthermore, 150 fish with a rate of 10–15 parasites/fish were fed for 21 days and the number
of gill parasites was recorded. All strains were sensitive to both compounds. PTSO showed the
highest inhibitory effect against all target strains, while PTS showed higher effectiveness against
S. chrysophrii. Fish from ALLIUM group presented the highest probability of survival, increasing
up to 91.1%, whereas in the control group, the probability of survival was 66.7%. The number of
parasites in the gilthead sea bream decreased in the ALLIUM group over time. These results suggest
the inclusion of PTS and PTSO in feed as a natural strategy to prevent antibacterial and antiparasitic
fish diseases.},
organization = {Centre for the Development of Industrial Technology (CDTI)	20170032
CER-20211010},
publisher = {MDPI},
keywords = {Photobacterium damselae},
keywords = {Sparicotyle chrysophrii},
keywords = {Antibacterial},
keywords = {Antiparasitic},
keywords = {Allium},
keywords = {Phytogenics},
title = {Antibacterial and Antiparasitic Activity of Propyl-Propane- Thiosulfinate (PTS) and Propyl-Propane-Thiosulfonate (PTSO) from Allium cepa against Gilthead Sea Bream Pathogens in In Vitro and In Vivo Studies},
doi = {10.3390/molecules27206900},
author = {Cabello Gómez, José F. and Aguinaga Casañas, María Arántzazu and Falcón Piñeiro, Ana and González Gragera, Elías and Márquez Martín, Raquel and Baños, Alberto and Martínez Bueno, Manuel},
}