@misc{10481/76963, year = {2022}, month = {8}, url = {https://hdl.handle.net/10481/76963}, abstract = {We report a platform combining multicomponent reaction synthesis and automated cell-based screening to develop biocompatible NIR-BODIPY fluorophores. From a library of over 60 fluorophores, we optimised compound NIRBD-62c as a multimodal probe with suitable properties for STED superresolution and fluorescence lifetime imaging. Furthermore, we employed NIRBD-62c for imaging trafficking inside cells and to examine how pharmacological inhibitors can alter the vesicular traffic between intracellular compartments and the plasma membrane.}, organization = {Fundacion Seneca 21124/SF/19 MCIN/AEI PID2020-114256RB-I00}, organization = {Spanish Government}, organization = {European Commission PID2019-107991RB-I00 European Research Council (ERC) European Commission 771443}, organization = {Royal Society of London}, organization = {European Commission RG160289}, publisher = {Royal Society of Chemistry}, title = {A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging}, doi = {10.1039/d2cb00168c}, author = {Fernández, Antonio and González García, María del Carmen and Espinar Barranco, Laura and González Vera, Juan Antonio and Orte Gutiérrez, Ángel}, }