@misc{10481/76734,
year = {2022},
month = {8},
url = {http://hdl.handle.net/10481/76734},
abstract = {In 2000 and 2011, Hanahan and Weinberg published two papers in which they defined the
characteristics that cells must fulfil in order to be considered neoplastic cells in all types of tumours
that affect humans, which the authors called “hallmarks of cancer”. These papers have represented a
milestone in our understanding of the biology of many types of cancers and have made it possible
to reach high levels of scientific evidence in relation to the prognostic impact that these hallmarks
have on different tumour types. However, to date, there is no study that globally analyses evidencebased
knowledge on the importance of these hallmarks in oral and oropharyngeal squamous cell
carcinomas. For this reason, we set out to conduct this scoping review of systematic reviews with
the aim of detecting evidence gaps in relation to the relevance of the cancer hallmarks proposed by
Hanahan andWeinberg in oral and oropharyngeal cancer, and oral potentially malignant disorders,
and to point out future lines of research in this field.},
publisher = {MDPI},
keywords = {Hallmarks of cancer},
keywords = {Biomarkers},
keywords = {Oral cancer},
keywords = {Oropharyngeal cancer},
keywords = {Oral potentially malignant disorders},
keywords = {Scoping review},
keywords = {Systematic review},
keywords = {Meta-analysis},
title = {Hallmarks of Cancer Applied to Oral and Oropharyngeal Carcinogenesis: A Scoping Review of the Evidence Gaps Found in Published Systematic Reviews},
doi = {10.3390/cancers14153834},
author = {González Moles, Miguel Ángel and López Ansio, María and Ramos García, Pablo},
}