@misc{10481/76626,
year = {2022},
month = {7},
url = {http://hdl.handle.net/10481/76626},
abstract = {The etiology of prostate cancer (PCa) remains uncertain, and the role of diet is unclear. We
aimed to evaluate the role of diet, through dietary patterns, on PCa, considering tumor aggressiveness
and extension. The CAPLIFE study is a population-based case-control study including a total of
428 incident PCa cases and 393 controls aged 40–80 years. Dietary information was collected through
a validated food frequency questionnaire. Three dietary patterns were identified through principal
component analysis: “Mediterranean,” “Western,” and “Unhealthy,” which were categorized into
tertiles according to the control group cutoff points. Tumor aggressiveness and extension was
determined. Logistic regression models were used to assess the association between dietary patterns
and PCa. High adherence to an unhealthy dietary pattern was associated with higher odds of PCa,
ORT3vsT1 = 1.52 (95% CI 1.02–2.27), especially for cases with ISUP 1–2 and localized PCa tumors. This
association was not observed with aWestern or Mediterranean pattern. In conclusion, adherence to
an unhealthy diet appears to be associated with higher odds of PCa, especially for cases with ISUP
1–2 and localized PCa tumors.},
organization = {Regional Ministry of Health and Families, Junta de Andalucia/Consejeria de Salud y Familias, Junta de Andalucia	PI-0514-2016},
publisher = {MDPI},
keywords = {Dietary patterns},
keywords = {Prostate cancer},
keywords = {CAPLIFE study},
keywords = {Case-control study},
keywords = {Principal component analysis},
title = {Dietary Patterns and Prostate Cancer: CAPLIFE Study},
doi = {10.3390/cancers14143475},
author = {Lozano Lorca, Macarena and Rodríguez González, Margarita and Salcedo Bellido, Inmaculada and Vázquez Alonso, Fernando and Arrabal Polo, Miguel Ángel and Martín Castaño, Benita and Sánchez Pérez, María José and Jiménez Moleón, José Juan and Olmedo Requena, María Rocío},
}