@misc{10481/75669,
year = {2022},
month = {5},
url = {http://hdl.handle.net/10481/75669},
abstract = {Scope Dairy consumption has been suggested to impact cognition; however, evidence is limited and inconsistent. This study aims to longitudinally assess the association between dairy consumption with cognitive changes in an older Spanish population at high cardiovascular disease risk. Methods and results Four thousand six hundred sixty eight participants aged 55-75 years, completed a validated food frequency questionnaire at baseline and a neuropsychological battery of tests at baseline and 2-year follow-up. Multivariable linear regression models are used, scaled by 100 (i.e., the units of beta correspond to 1 SD/100), to assess associations between baseline tertile daily consumption and 2-year changes in cognitive performance. Participants in the highest tertile of total milk and whole-fat milk consumption have a greater decline in global cognitive function (beta: -4.71, 95% CI: -8.74 to -0.69, p-trend = 0.020 and beta: -6.64, 95% CI: -10.81 to -2.47, p-trend = 0.002, respectively) compared to those in the lowest tertile. No associations are observed between low fat milk, yogurt, cheese or fermented dairy consumption, and changes in cognitive performance. Conclusion Results suggest there are no clear prospective associations between consumption of most commonly consumed dairy products and cognition, although there may be an association with a greater rate of cognitive decline over a 2-year period in older adults at high cardiovascular disease risk for whole-fat milk.},
organization = {CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN)},
organization = {Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS) - European Regional Development Fund	PI13/00673	
PI13/00492	
PI13/00272	
PI13/01123	
PI13/00462	
PI13/00233	
PI13/02184	
PI13/00728	
PI13/01090	
PI13/01056	
PI14/01722	
PI14/00636	
PI14/00618	
PI14/00696	
PI14/01206	
PI14/01919	
PI14/00853	
PI14/01374	
PI14/00972	
PI14/00728	
PI14/01471	
PI16/00473},
organization = {Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant},
organization = {European Research Council (ERC)
European Commission	340918	
2013ACUP00194},
organization = {Junta de Andalucia	PI0458/2013	
PS0358/2016	
PI0137/2018},
organization = {Center for Forestry Research & Experimentation (CIEF)},
organization = {European Commission	PROMETEO/2017/017	
PROMETEO/2021/021	
SEMERGEN grant},
organization = {Juan de la Cierva-Incorporacion research grant of the Spanish Ministry of Economy, Industry and Competitiveness	IJC2019-042420-I},
organization = {European Social Fund (ESF)		
EU-H2020 Grants	Eat2beNICE/H2020-SFS-2016-2	
Horizon 2020 PRIME study (Prevention and Remediation of Insulin Multimorbidity in Europe	847879},
organization = {Spanish Government	FPU 20/00385	
FPU 17/01925},
organization = {Canadian Institutes of Health Research (CIHR)},
organization = {University of Rovira I Virgili	2020PMF-PIPF-37},
organization = {ICREA under the ICREA Academia program},
organization = {'Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS) - European Regional Development Fund'	PI16/00662	
PI16/01873	
PI16/01094	
PI16/00501	
PI16/00533	
PI16/00381	
PI16/00366	
PI16/01522	
PI16/01120	
PI17/00764	
PI17/01183	
PI17/00855	
PI17/01347	
PI17/00525	
PI17/01827	
PI17/00532	
PI17/00215	
PI17/01441	
PI17/00508	
PI17/01732	
PI17/00926	
PI19/00957	
PI19/00386	
the Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS) - European Regional Development Fund	PI19/00309	
PI19/01032	
PI19/00576	
PI19/00017	
PI19/01226	
PI19/00781	
PI19/01560	
PI19/01332	
PI20/01802	
PI20/00138	
PI20/01532	
PI20/00456	
PI20/00339	
PI20/00557	
PI20/00886	
PI20/01158},
publisher = {Wiley},
keywords = {Cognition},
keywords = {Cognitive decline},
keywords = {Dairy},
keywords = {Milk},
keywords = {PREDIMED-Plus},
title = {Dairy Product Consumption and Changes in Cognitive Performance: Two-Year Analysis of the PREDIMED-Plus Cohort},
doi = {10.1002/mnfr.202101058},
author = {Ni, Jiaqi and Bueno Cavanillas, Aurora and Predimed-Plus Investigators},
}