@misc{10481/75668,
year = {2022},
month = {5},
url = {http://hdl.handle.net/10481/75668},
abstract = {Nannochloropsis gaditana is a microalga with interesting nutritional and functional value
due to its high content of protein, polyunsaturated fatty acids, and bioactive compounds. However,
the hardness of its cell wall prevents accessibility to these components. This work aimed to study
the effect of a treatment to increase the fragility of the cell wall on the bioavailability of its nutrients
and functional compounds. The antioxidant and antiproliferative capacity of functional extracts
from treated and untreated N. gaditana was assessed, and the profile of bioactive compounds was
characterized. Furthermore, to study the effect of treatment on its nutrient availability and functional
capacity, an in vivo experiment was carried out using a rat experimental model and a 20% dietary
inclusion level of microalgae. Functional extracts from treated N. gaditana exhibited higher antioxidant
activity than the untreated control. Furthermore, the treated microalga induced hypoglycemic action,
higher nitrogen digestibility, and increased hepatic antioxidant activity. In conclusion, N. gaditana
has interesting hepatoprotective, antioxidant, and anti-inflammatory potential, thus proving itself an
ideal functional food candidate, especially if the microalga is treated to increase the fragility of its cell
wall before consumption.},
organization = {International Excellence Campus of the Sea (CEI-MAR)	CEIJ-016},
organization = {Spanish Government		
European Commission	RTC-2017-6540-1	
RTI-2018-100934-B-I00},
publisher = {MDPI},
keywords = {Nannochloropsis gaditana},
keywords = {Functional extracts},
keywords = {Nutrient bioavailability},
keywords = {Antioxidant capacity},
title = {In Vivo Nutritional Assessment of the Microalga Nannochloropsis gaditana and Evaluation of the Antioxidant and Antiproliferative Capacity of Its Functional Extracts},
doi = {10.3390/md20050318},
author = {Martínez Martínez, Rosario and García Beltrán, Alejandro and Kapravelou, Garyfallia and Mesas Hernández, Cristina and Cabeza Montilla, Laura and Perazzoli, Gloria and Galisteo Moya, Milagros and Aranda Ramírez, Pilar and Prados Salazar, José Carlos and López-Jurado Romero De La Cruz, María and Melguizo Alonso, Consolación and Porres Foulquie, Jesús María},
}