@misc{10481/75187,
year = {2022},
month = {4},
url = {http://hdl.handle.net/10481/75187},
abstract = {Objective: Autism spectrum disorders (ASDs) appear in the early stages of neurodevelopment,
and they remain constant throughout life. Currently, due to limitations in ASDs treatment,
alternative approaches, such as nutritional interventions, have frequently been implemented. The
aim of this narrative review is to gather the most relevant and updated studies about dietary interventions
related to ASDs etiopathogenesis. Results: Our literature search focused on the gluten- and
casein-free (GFCF) diet. The literature found shows the inexistence of enough scientific evidence
to support a general recommendation of dietary intervention in children with ASD. Protocols and
procedures for assessing risk and safety are also needed. Future lines: Prospective and controlled
research studies with larger sample sizes and longer follow-up times are scarce and needed. In addition,
studies considering an assessment of intestinal permeability, bacterial population, enzymatic,
and inflammatory gastrointestinal activity are interesting to identify possible responders. Besides
brain imaging techniques, genetic tests can also contribute as markers to evaluate the comorbidity of
gastrointestinal symptoms.},
organization = {University of Granada	CTS549},
publisher = {MDPI},
keywords = {Diet},
keywords = {Gluten},
keywords = {Casein},
keywords = {Autism spectrum disorders},
title = {A Narrative Review about Autism Spectrum Disorders and Exclusion of Gluten and Casein from the Diet},
doi = {10.3390/nu14091797},
author = {González Domenech, Pablo José and Díaz Atienza, Francisco and Gutiérrez Rojas, Luis and Fernández Soto, María Luisa},
}