@misc{10481/74547,
year = {2022},
month = {4},
url = {http://hdl.handle.net/10481/74547},
abstract = {Purpose To assess the association between three different a priori dietary patterns adherence (17-item energy reduced-
Mediterranean Diet (MedDiet), Trichopoulou-MedDiet and Dietary Approach to Stop Hypertension (DASH)), as well as
the Protein Diet Score and kidney function decline after one year of follow-up in elderly individuals with overweight/obesity
and metabolic syndrome (MetS).
Methods We prospectively analyzed 5675 participants (55–75 years) from the PREDIMED-Plus study. At baseline and at
one year, we evaluated the creatinine-based estimated glomerular filtration rate (eGFR) and food-frequency questionnairesderived
dietary scores. Associations between four categories (decrease/maintenance and tertiles of increase) of each dietary
pattern and changes in eGFR (ml/min/1.73m2) or ≥ 10% eGFR decline were assessed by fitting multivariable linear or logistic
regression models, as appropriate.
Results Participants in the highest tertile of increase in 17-item erMedDiet Score showed higher upward changes in eGFR
(β: 1.87 ml/min/1.73m2; 95% CI: 1.00–2.73) and had lower odds of ≥ 10% eGFR decline (OR: 0.62; 95% CI: 0.47–0.82)
compared to individuals in the decrease/maintenance category, while Trichopoulou-MedDiet and DASH Scores were not
associated with any renal outcomes. Those in the highest tertile of increase in Protein Diet Score had greater downward
changes in eGFR (β: − 0.87 ml/min/1.73m2; 95% CI: − 1.73 to − 0.01) and 32% higher odds of eGFR decline (OR: 1.32;
95% CI: 1.00–1.75).
Conclusions Among elderly individuals with overweight/obesity and MetS, only higher upward change in the 17-item
erMedDiet score adherence was associated with better kidney function after one year. However, increasing Protein Diet Score
appeared to have an adverse impact on kidney health. Trial Registration Number: ISRCTN89898870 (Data of registration:
2014).},
organization = {CRUE-CSIC agreement},
organization = {Springer Nature},
organization = {CIBER Fisiopatologia de la Obesidad y Nutricion (CIBEROBN)},
organization = {Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS)},
organization = {European Commission	PI13/00673	
PI13/00492	
PI13/00272	
PI13/01123	
PI13/00462	
PI13/00233	
PI13/02184	
PI13/00728	
PI13/01090	
PI13/01056	
PI14/01722	
PI14/00636	
PI14/00618	
PI14/00696	
PI14/01206	
PI14/01919	
PI14/00853	
PI14/01374	
PI14/00972	
PI14/00728},
organization = {The European Regional Development Fund	PI14/01471	
PI16/00473	
PI16/00662	
PI16/01873	
PI16/01094	
PI16/00501	
PI16/00533	
PI16/00381	
PI16/00366	
PI16/01522	
PI16/01120	
PI17/00764	
PI17/01183	
PI17/00855	
PI17/01347	
PI17/00525	
PI17/01827	
PI17/00532},
organization = {European Commission	PI19/01226	
PI19/00781	
PI19/01560	
PI19/01332	
PI20/01802	
PI20/00138	
PI20/01532	
PI20/00456	
PI20/00339	
PI20/00557	
PI20/00886	
PI20/01158},
organization = {Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus grant},
organization = {European Research Council (ERC)},
organization = {European Commission	340918},
organization = {Recercaixa grant	2013ACUP00194},
organization = {Junta de Andalucia	PI0458/2013	
PS0358/2016	
PI0137/2018},
organization = {Generalitat Valenciana},
organization = {European Commission},
organization = {General Electric	PROMETEO/2017/017	
PROMETEO 21/2021	
SEMERGEN grant},
organization = {Boosting young talent call grant program for the development of IISPV research projects 2019-2021	2019/IISPV/03},
organization = {Societat Catalana d'Endocrinologia i Nutricio (SCEN) Clinical-Research Grant 2019},
organization = {CIBEROBN entitled: Lifestyle Interventions and Chronic Kidney Disease: Inflammation, Oxidative Stress and Metabolomic Profile (LIKIDI study) grant},
organization = {ICREA},
organization = {Spanish Government	FPU17/06488},
organization = {European Commission	PI17/00215	
PI17/01441	
PI17/00508	
PI17/01732	
PI17/00926	
PI19/00957	
PI19/00386	
PI19/00309	
PI19/01032	
PI19/00576	
PI19/00017},
publisher = {Springer},
keywords = {Dietary patterns},
keywords = {Mediterranean diet},
keywords = {DASH diet},
keywords = {Protein diet score},
keywords = {Kidney function},
keywords = {Glomerular filtration rate},
title = {Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk},
doi = {10.1007/s00394-022-02838-7},
author = {Valle Hita, Cristina and Cano Ibáñez, Naomi},
}