@misc{10481/72943,
year = {2021},
month = {11},
url = {http://hdl.handle.net/10481/72943},
abstract = {By applying a combination of the coupling-and-decoupling (CAD) chemistry of the vinyl sulfonate group with the click thia-Michael addition to the vinyl sulfone group (MAVS) we performed the irreversible unidirectional transportation of the ring through the linear component in a [2]rotaxane by a chemically and pH-driven flashing energy ratchet mechanism. The design is based on a monostoppered thread precursor bearing a sulfonate stopper, a vinyl sulfone group on the unstoppered end and a dibenzylammonium unit as recognition site for the dibenzo-24-crown-8 macrocycle. First, the ring enters from the vinyl sulfone side and the rotaxane is capped through a thia-Michael addition reaction. Then, the cleavage of the sulfonate group of the opposite stopper using MgBr2 as chemical stimulus and subsequent addition of base (Et3N) promoted the controlled and directional release of the macrocycle into the bulk under mild conditions. The efficiency of the system allowed the in situ operation as demonstrated by NMR and HRMS techniques.},
organization = {FEDER(EDRF)/Junta de Andalucia-Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades - MCIN/AIE	P18-FR-2877},
organization = {Ministerio de Economia y Competitividad (MINECO, Spain) (FEDER funds)	CTQ2014-55474-C2-2-R;
CTQ2017-86125P},
organization = {Universidad de Granada},
organization = {RSC},
organization = {MCIN/AIE	PID2020-112906GA-I00},
publisher = {Royal Society of Chemistry},
title = {Vinyl sulfonyl chemistry-driven unidirectional transport of a macrocycle through a [2]rotaxane},
doi = {10.1039/D1QO01491A},
author = {H. G David, Arthur and García Cerezo, Pablo and González Campaña, Araceli and Santoyo González, Francisco and Blanco Suárez, Víctor},
}