@misc{10481/72934,
year = {2022},
month = {5},
url = {http://hdl.handle.net/10481/72934},
abstract = {A microfluidic paper-based analytical device integrating a chromoreactand – a formylazo dye– has been fabri- cated and used for a colorimetric assay of sulfites. The chromoreactand was covalently linked to paper by vinyl sulfone chemistry. This work presents two robust capillary microfluidic devices to determine sulfite in wine without any pretreatment. One of them based on thread (µTPAD) useful to determine it in white wine and another based on paper (µPAD) to specifically determine sulfite in red wine as well as in white wine. Both are based on the selective recognition of sulfite by means of a chromoreactand that turns from orange to yellow in the presence of sulfite. The colour information acquired (H coordinate) using a digital camera readout allows for a range of appli-
cation of the µTPAD from 7.8⋅10−5 M (8.1 mg L−1) to 2.7⋅10−3 M (279.3 mg L−1) with a limit of detection (LOD) of 78 µM. The strong interference caused by the dyes present in red wine is eliminated by including a laminated paper
channel in the µPAD structure that allows for the separation of colorants from red wine before the recognition of the sulfite. This makes it possible to adjust the µPAD procedure to the usual sulfite concentration in wine, with an LOD of 2.2⋅10−4 M (22.7 mg L−1) and a CV of 2.6%.},
organization = {This work was founded by Spanish “Ministerio de Economía y Competitividad” (Projects PID2019-103938RB-I00) and Junta de
Andalucía (Projects B-FQM-243-UGR18 and P18-RT-2961). The projects were partially supported by European Regional Development Funds (ERDF).},
keywords = {µPAD},
keywords = {Sulfite determination},
keywords = {Colorimetry},
keywords = {Wine analysis},
keywords = {Point-of-need},
keywords = {µTPAD},
title = {Capillary microfluidic platform for sulfite determination in wines},
doi = {https://doi.org/10.1016/j.snb.2022.131549},
author = {Arroyo, Manuel J. and Orbe Payá, Ignacio De and Ortega Muñoz, Mariano and Vilar Tenorio, Jose and Gallego, David and Mohr, Gerhard J and Capitán Vallvey, Luis Fermín and Erenas Rodríguez, Miguel María},
}