@misc{10481/72658,
year = {2021},
month = {3},
url = {http://hdl.handle.net/10481/72658},
abstract = {Background Non-adherence
to medications continues
to be a burden worldwide, with significant negative
consequences. Community pharmacist interventions seem
to be effective at improving medication adherence. However,
more evidence is needed regarding their impact on disease-specific
outcomes. The aim was to evaluate the impact
of a community pharmacist-led
adherence management
intervention on adherence and clinical outcomes in
patients with hypertension, asthma and chronic obstructive
pulmonary disease (COPD).
Methods A 6-month
cluster randomised controlled
trial was conducted in Spanish community pharmacies.
Patients suffering from hypertension, asthma and COPD
were recruited. Patients in the intervention group received
a medication adherence management intervention and
the control group received usual care. The intervention
was based on theoretical frameworks for changing patient
behaviour. Medication adherence, disease-specific
outcomes
(Asthma Control Questionnaire (ACQ) scores, Clinical COPD
Questionnaire (CCQ) scores and blood pressure levels) and
disease control were evaluated. A multilevel regression model
was used to analyse the data.
Results Ninety-eight
pharmacies and 1186 patients were
recruited, with 1038 patients completing the study. Patients
receiving the intervention had an OR of 5.12 (95% CI 3.20
to 8.20, p<0.05) of being adherent after the 6 months. At
the end of the study, patients in the intervention group had
lower diastolic blood pressure levels (mean difference (MD)
−2.88, 95% CI −5.33 to −0.43, p=0.02), lower CCQ scores
(MD −0.50, 95% CI −0.82 to −0.18, p<0.05) and lower
ACQ scores (MD −0.28, 95% CI −0.56 to 0.00, p<0.05)
when compared with the control group.
Conclusions A community pharmacist-led
medication
adherence intervention was effective at improving
medication adherence and clinical outcomes in patients
suffering from hypertension, asthma and COPD. Future
research should explore the implementation of these
interventions in routine practice.},
organization = {Laboratorios Cinfa},
publisher = {BMJ},
title = {Effectiveness of a medication adherence management intervention in a community pharmacy setting: a cluster randomised controlled trial},
doi = {10.1136/bmjqs-2020-011671},
author = {Torres Robles, Andrea and Benrimoj, Shalom Isaac and Gastelurrutia Garralda, Miguel Ángel and Martínez Martínez, Fernando and Pérez Escamilla, Beatriz and Valverde Merino, María Isabel},
}