@misc{10481/72282,
year = {2022},
month = {1},
url = {http://hdl.handle.net/10481/72282},
abstract = {Background & aims: The specific association of olive oil consumption with coronary heart disease (CHD) or stroke has not been totally established. Objective: to examine whether olive oil consumption is associated with subclinical atherosclerosis, the risk of total cardiovascular disease (CVD), CHD, and stroke. Methods: Three cohorts were included: AWHS (2318 men), SUN Project (18,266 men and women), and EPIC-Spain (39,393 men and women). Olive oil consumption was measured at baseline using validated questionnaires. Results: In the AWHS, 747 participants had a positive coronary artery calcium score (CACS>0), and the OR (95% CI) was 0.89 (0.72, 1.10) in those with virgin olive oil consumption ≥30 g/day (v. <10 g/day). In the SUN Project (follow-up 10.8 years) 261 total CVD cases occurred, and the HR was 0.57 (0.34, 0.96) for consumptions ≥30 g/day (v. <10 g/day). In the EPIC-Spain (follow-up 22.8 years) 1300 CHD cases and 938 stroke cases occurred; the HRs for stroke according, 0 to <10 (ref), 10 to <20, 20 to <30, and ≥30 g/day of olive oil consumption, were 0.84 (0.70, 1.02), 0.80 (0.66, 0.96), 0.89 (0.74, 1.07). A weaker association was observed for CHD. The association was stronger among those consuming virgin olive oil, instead of common (refined). Conclusions: Olive oil is associated with lower risk of CVD and stroke. The maximum benefit could be obtained with a consumption between 20 and 30 g/day. The association could be stronger for virgin olive oil and might operate from the early stages of the disease.},
organization = {CIBERESP},
organization = {State Secretary of R+D+I},
organization = {Faculty of Science and Engineering, University of Manchester},
organization = {Plan Nacional sobre Drogas

	2020/021},
organization = {Instituto de Salud Carlos III},
organization = {European Regional Development Fund},
organization = {Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares},
organization = {Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición},
publisher = {Elsevier},
keywords = {Mediterranean countries},
keywords = {Olive oil},
keywords = {Cardiovascular disease},
title = {Olive oil consumption is associated with a lower risk of cardiovascular disease and stroke},
doi = {10.1016/j.clnu.2021.11.002},
author = {Molina Montes, María Ester and Sánchez Pérez, María José},
}