@misc{10481/71511,
year = {2021},
month = {9},
url = {http://hdl.handle.net/10481/71511},
abstract = {Adequate nutrition is vital for immune homeostasis. However, the incidence of obesity is increasing worldwide due to the adoption of the Western
diet and a sedentary lifestyle. Obesity is associated with chronic inflammation which alters the function of adipose tissue, liver, pancreas, and the nervous
system. Inflammation is related to cellular senescence, distinguished by irreversible cell cycle arrest. Senescent cells secrete the senescence-associated
secretory phenotype (SASP) which contains pro-inflammatory factors. Targeting processes in senescence might have a salutary approach to obesity. The
present review highlights the impact of an unhealthy diet on tissues affected by obesity, and the mechanisms that promote the consequent inflammation
and senescence.},
organization = {UGR Plan Propio de Investigación 2016},
organization = {Excellence actions: Unit of Excellence on Exercise and Health (UCEES), University of Granada},
organization = {“Fundación Ramón Are- ces”, Madrid, Spain.},
organization = {Universidad de Granada / CBUA},
publisher = {Elsevier},
keywords = {Aging},
keywords = {Diet},
keywords = {Inflammation},
keywords = {Microbiota obesity},
keywords = {Senescence},
title = {Nutrition and cellular senescence in obesity-related disorders},
doi = {10.1016/j.jnutbio.2021.108861},
author = {Rubio Tomás, Teresa and Rueda Robles, Ascensión and Plaza Díaz, Julio and Álvarez Mercado, Ana Isabel},
}