@misc{10481/71272,
year = {2021},
url = {http://hdl.handle.net/10481/71272},
abstract = {Development of cataracts is a well-known adverse effect of ionizing radiation, but little
information is available on their incidence in patients after other medical procedures, such as cardiac
catheterizations. The study objective was to determine the incidence of cataracts in a cohort of patients
undergoing percutaneous coronary intervention (PCI) for chronic coronary total occlusion (CTO) and
its association with radiation dose. The study analyzed the incidence of cataracts during the follow-up
of 126 patients who underwent chronic total coronary PCI, using Cox regression to identify predictive
factors of cataract development. The study included 126 patients, 86.9% male, with a mean age of
60.5 years (range, 55.0–68.0 years). Twenty-three (18.2% n = 23) developed cataracts during a mean
follow-up of 49.5 months (range 37.3–64.5 months). A higher incidence was observed in patients
who received more than 5 Gy (29.0% vs. 14.7%, Hazard ratio (HR = 2.84 [1.19–6.77]). Multivariate
analysis revealed a relationship between cataract development during the follow-up and a receipt of
radiation dose >5 Gy (HR = 2.60, 95% confidence interval [CI 1.03–6.61]; p = 0.03), presence or history
of predisposing eye disease (HR = 4.42, CI:1.57–12.40), diabetes (HR = 3.33 [1.22–9.24]), and older
age, as in >57 (HR, 6.40 [1.81–22.61]). An elevated incidence of cataracts was observed in patients
after PCI for CTO. The onset of cataracts is related to the radiation dose during catheterization, which
is a potentially avoidable effect of which operators should be aware.},
publisher = {MDPI},
keywords = {Cataracts},
keywords = {Ionizing radiation},
keywords = {Chronic coronary total occlusion},
keywords = {Percutaneous coronary intervention},
title = {High Incidence of Cataracts in the Follow-Up of Patients Undergoing Percutaneous Coronary Intervention for Chronic Coronary Total Occlusion},
doi = {10.3390/jcm10215002},
author = {Rivera López, Ricardo Francisco and García López, Celia and Moreno Sánchez, José María and Rivera López, Rafael A. and Almansa López, Julio and Rivera Fernández, Ricardo and Molina Navarro, Eduardo and Jiménez Fernández, Miriam and Ortiz Pérez, Santiago and Ramírez Hernández, José Antonio},
}