@misc{10481/69272,
year = {2021},
month = {6},
url = {http://hdl.handle.net/10481/69272},
abstract = {The constrained total energy expenditure (TEE) model posits that progressive increases in physical activity (PA) lead to increases in TEE; but after certain PA threshold, TEE plateaus. Then, a compensatory reduction in the expenditure of non-essential activities constrains the TEE. We hypothesized that high PA levels as locomotion associate with a compensatory attenuation in arm movements. We included 209 adults (64% females, mean [SD] age 32.1 [15.0] years) and 105 children (40% females, age 10.0 [1.1] years). Subjects wore, simultaneously, one accelerometer in the non-dominant wrist and another in the hip for ≥ 4 days. We analyzed the association between wrist-measured (arm movements plus locomotion) and hip-measured PA (locomotion). We also analyzed how the capacity to dissociate arm movements from locomotion influences total PA. In adults, the association between wrist-measured and hip-measured PA was better described by a quadratic than a linear model (Quadratic-R2 = 0.54 vs. Linear-R2 = 0.52; P = 0.003). Above the 80th percentile of hip-measured PA, wrist-measured PA plateaued. In children, there was no evidence that a quadratic model fitted the association between wrist-measured and hip-measured PA better than a linear model (R2 = 0.58 in both models, P = 0.25). In adults and children, those with the highest capacity to dissociate arm movements from locomotion—i.e. higher arm movements for a given locomotion—reached the highest total PA. We conclude that, in adults, elevated locomotion associates with a compensatory reduction in arm movements (probably non-essential fidgeting) that partially explains the constrained TEE model. Subjects with the lowest arm compensation reach the highest total PA.},
organization = {AstraZeneca HealthCare Foundation
	PTA 12264-I},
organization = {EXERNET Research Network on Exercise and Health in Special Populations
	DEP2005-00046/ACTI},
organization = {Fundación Iberoamericana de Nutrición},
organization = {Fondo Nacional de Desarrollo Científico y Tecnológico

11180361	FONDECYT},
organization = {Ministerio de Economía y Competitividad

	MINECO},
organization = {Instituto de Salud Carlos III

PI13/01393	ISCIII},
organization = {Universidad de Granada

	UGR},
organization = {European Regional Development Fund

RD16/0022,SOMM17/6107/UGR	ERDF},
organization = {Consejería de Conocimiento, Investigación y Universidad, Junta de Andalucía},
organization = {Vicerrectorado de Investigación y Transferencia, Universidad de Granada Health [UCEES]),Plan Propio de Investigación 2016 (Excellence actions: Unit of Excellence on Exercise,Plan Propio de Investigación 2019 (Programa Contratos-Puente)},
publisher = {Springer Nature},
title = {Deciphering the constrained total energy expenditure model in humans by associating accelerometer‑measured physical activity from wrist and hip},
doi = {10.1038/s41598-021-91750-x},
author = {Fernández‑Verdejo, Rodrigo and Alcántara Alcántara, Juan Manuel and Galgani, José E. and Acosta Manzano, Francisco Miguel and Migueles Hidalgo, Jairo and Amaro Gahete, Francisco José and Labayen, Idoia and Ortega Porcel, Francisco Bartolomé and Ruiz Ruiz, Jonatan},
}