@misc{10481/69027,
year = {2021},
url = {http://hdl.handle.net/10481/69027},
abstract = {Limosilactobacillus reuteri INIA P572 is a strain able to produce the antimicrobial compound
reuterin in dairy products, exhibiting a protective effect against some food-borne pathogens. In this
study, we investigated some probiotic properties of this strain such as resistance to gastrointestinal
passage or to colonic conditions, reuterin production in a colonic environment, and immunomodulatory activity, using different in vitro and in vivo models. The results showed a high resistance
of this strain to gastrointestinal conditions, as well as capacity to grow and produce reuterin in a
human colonic model. Although the in vitro assays using the RAW 264.7 macrophage cell line did
not demonstrate direct immunomodulatory properties, the in vivo assays using a Dextran Sulphate
Sodium (DSS)-induced colitic mice model showed clear immunomodulatory and protective effects of
this strain.},
publisher = {MDPI},
keywords = {Limosilactobacillus reuteri},
keywords = {Probiotics},
keywords = {Colonic model},
keywords = {DSS-induced colitic model},
keywords = {Immunomodulation},
keywords = {Reuterin},
keywords = {Protective effect},
title = {Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572},
doi = {10.3390/nu13061860},
author = {Díez Echave, Patricia and Garrido-Mesa, José and Vezza, Teresa and Hidalgo García, Laura and Algieri, Francesca and Rodríguez Nogales, Alba and Rodríguez Cabezas, María Elena and Gálvez Peralta, Julio Juan},
}