@misc{10481/68521,
year = {2021},
url = {http://hdl.handle.net/10481/68521},
abstract = {We aimed to assess the influence of the Mediterranean Diet adherence and physical activity
(PA) on body composition, with a particular focus on bone health, in young patients with celiac
disease (CD). The CD group (n = 59) included children with CD with a long (>18 months, n = 41)
or recent (<18 months, n = 18) adherence to a gluten-free diet (GFD). The non-celiac group (n = 40)
included non-celiac children. After adjusting for potential confounders, the CD group showed lower
body weight (p = 0.034), lean mass (p = 0.003), bone mineral content (p = 0.006), and bone Z-score
(p = 0.036) than non-celiac children, even when the model was further adjusted for adherence to
a GFD for at least 18 months. Among CD children, spending greater time in vigorous physical
activity was associated with higher lean mass (p = 0.020) and bone mineral density with evidence of
statistical significance (p = 0.078) regardless of the time they followed a GFD. In addition, a greater
Mediterranean Diet adherence was associated with a higher bone Z-score (p = 0.020). Moreover, lean
mass was strongly associated with bone mineral density and independently explained 12% of its
variability (p < 0.001). These findings suggest the importance of correctly monitoring lifestyle in
children with CD regarding dietary habits and PA levels to improve lean mass and, consequently,
bone quality in this population.},
organization = {Regional Government of Andalusia, Excellence Research
Project No P12-AGR-2581},
organization = {Project from the University of Granada Ref. PP2017-PIP14},
organization = {Spanish Ministry of Education, Culture, and Sports (Grant number
FPU17/03715)},
publisher = {MDPI},
keywords = {Celiac disease},
keywords = {Gluten-free diet},
keywords = {Mediterranean diet},
keywords = {Children},
keywords = {Body composition},
title = {Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet},
doi = {10.3390/nu13051636},
author = {Nestares Pleguezuelo, María Teresa and Bonillo Leon, Rocío and Maldonado Lozano, José and De la Flor Alemany, Marta and Aparicio García-Molina, Virginia},
}