@misc{10481/68455,
year = {2021},
url = {http://hdl.handle.net/10481/68455},
abstract = {This study aimed to examine the association of relative handgrip strength (rHGS) with
cardiometabolic disease risk factors in women with systemic lupus erythematosus (SLE). Methods:
Seventy-seven women with SLE (mean age 43.2, SD 13.8) and clinical stability during the previous
six months were included. Handgrip strength was assessed with a digital dynamometer and rHGS
was defined as absolute handgrip strength (aHGS) divided by body mass index (BMI). We measured
blood pressure, markers of lipid and glucose metabolism, inflammation (high sensitivity C-reactive
protein [hs-CRP]), arterial stiffness (pulse wave velocity [PWV]), and renal function. A clustered
cardiometabolic risk index (z-score) was computed. Results: Pearson0
s bivariate correlations revealed
that higher rHGS was associated with lower systolic blood pressure (SBP), triglycerides, hs-CRP, PWV,
and lower clustered cardiometabolic risk (rrange = from −0.43 to −0.23; all p < 0.05). Multivariable
linear regression analyses adjusted for age, disease activity (SLEDAI), and accrual damage (SDI)
confirmed these results (all p < 0.05) except for triglycerides. Conclusions: The findings suggest that
higher rHGS is significantly associated with lower cardiometabolic risk in women with SLE.},
organization = {Consejería de Salud, Junta de Andalucía (grant numbers:
PI-0525-2016 and PIER-0223-2019)},
organization = {Spanish Ministry of Education
(FPU15/00002)},
organization = {Spanish Ministry of Science, Innovation and Universities
(FPU18/01107)},
organization = {Gerty Cory pre-doctoral program for deficit areas at the University
of Almería},
publisher = {MDPI},
keywords = {Autoimmune diseases},
keywords = {Cardiovascular risk},
keywords = {Muscle strength},
keywords = {Body mass index},
keywords = {Metabolism},
keywords = {Cardiovascular disease},
keywords = {Lupus},
keywords = {Risk factors},
title = {Relative Handgrip Strength as Marker of Cardiometabolic Risk in Women with Systemic Lupus Erythematosus},
doi = {10.3390/ijerph18094630},
author = {Sola Rodríguez, Sergio and Gavilán Carrera, Blanca and Ortego Centeno, Norberto},
}