@misc{10481/67868,
year = {2021},
month = {1},
url = {http://hdl.handle.net/10481/67868},
abstract = {Pressurized liquid extraction (PLE) is a clean and environmentally friendly alternative
for the recovery of bioactive compounds from fruit by-products. Herein we focused on PLE for
the extraction of bioactive compounds from pomegranate peel using a combination of pressurized
water and ethanol. The main aim was to determine the optimal PLE conditions, i.e., ethanol percentage
and process temperature, to obtain a pomegranate peel extract (PPE) with maximum total
phenolic content (TPC), punicalagin content, and antimicrobial activity (AMA). The experimental
design was conducted using a central composite design with axial points. Response surface
methodology was applied to optimize the response variables using the desirability function. Multiple
response optimization indicated a process temperature of 200  C and ethanol of 77% as optimal
conditions. The TPC and the punicalagin content of PPE-PLE obtained under optimal conditions
were 164.3   10.7 mg GAE/g DW and 17   3.6 mg/g DW, respectively. Our findings support the
efficacy of PLE on TPC recovery but not in punicalagin recovery. The AMA against S. aureus was
14 mm. The efficacy of PPE-PLE in food applications must continue to be studied in order to achieve
adequate information on its potential for developing new food additives.},
organization = {Comisión Nacional de Investigación Científica y Tecnológica (CONICYT)

CONICYT FONDECYT

11160541},
publisher = {Mdpi},
keywords = {Pomegranate by-products},
keywords = {Pomegranate peel extract},
keywords = {Polyphenols},
keywords = {Punicalagin},
keywords = {Antioxidant},
keywords = {RSM},
title = {Recovery of Bioactive Compounds from Pomegranate (Punica granatum L.) Peel Using Pressurized Liquid Extraction},
doi = {10.3390/foods100 20203},
author = {García, Paula and Lozano Sánchez, Jesús and Leyva Jiménez, Francisco Javier},
}