@misc{10481/64408, year = {2020}, month = {8}, url = {http://hdl.handle.net/10481/64408}, abstract = {This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an aggressive virus, speci cally the so-called SARS{CoV{2 Severe Acute Respiratory Syndrome; corona virus n.2. The study is developed within a multiscale framework accounting for the interaction of di erent spatial scales, from the small scale of the virus itself and cells, to the large scale of individuals and further up to the collective behaviour of populations. An interdisciplinary vision is developed thanks to the contributions of epidemiologists, immunologists and economists as well as those of mathematical mod- ellers. The rst part of the contents is devoted to understanding the complex features of the system and to the design of a modelling rationale. The modelling approach is treated in the second part of the paper by showing both how the virus propagates into infected individuals, successfully and not successfully recovered, and also the spatial patterns, which are subsequently studied by kinetic and lattice models. The third part reports the contribution of research in the elds of virology, epidemiology, immune competition, and economy focussed also on social behaviours. Finally, a critical analysis is proposed looking ahead to research perspectives.}, organization = {Granada University}, organization = {modelling Nature Group, Spain}, organization = {Italian Research Council, IMATI, CNR, Pavia, Italy}, organization = {Engineering & Physical Sciences Research Council (EPSRC) EP/R023204/1}, organization = {Royal Society Wolfson Fellowship RSWF\R1\180009}, organization = {European Union (EU) 822781}, organization = {Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) PIP 11220150100500CO}, organization = {Secretaria de Ciencia y TecnologĂ­a (SECYT) 33620180100326CB}, organization = {National Science Foundation (NSF) DMS-1763272}, organization = {Simons Foundation for a NSF-Simons Center for Multiscale Cell Fate Research 594598QN}, organization = {United States Department of Health & Human Services National Institutes of Health (NIH) - USA 1U54CA217378-01A1 P30CA062203}, organization = {110145}, organization = {110146}, organization = {DMS-1714973}, organization = {DMS-1936833}, publisher = {World Scientific Publ CO}, keywords = {COVID-19}, keywords = {Living systems}, keywords = {Immune competition}, keywords = {Complexity}, title = {A multiscale model of virus pandemic: Heterogeneous interactive entities in a globally connected world}, doi = {10.1142/S0218202520500323}, author = {Bellomo, Nicola}, }