@misc{10481/63929,
year = {2020},
month = {8},
url = {http://hdl.handle.net/10481/63929},
abstract = {Patients frequently experience a weight gain after organ transplantation. This increase in weight is the
result of multiple factors, and is usually intensified by glucocorticoids and immunosuppressive drugs. It
can also delay graft function and cause serious health problems. The objective of this study was to study
the obesity as well as its causes and consequences in kidney transplant patients. The sample population
consisted of 282 renal transplant patients, 170 men and 112 women, 18-74 years of age, who were
monitored over a period of five years. For the purposes of our research, the patients were divided into
two groups: (1) normal weight 18.5 ≤ BMI <25; (2) overweight 25 ≤ BMI ≤30. The association between
BMI as an independent variable and graft survival was determined by means of a Cox regression analysis.
Overweight patients were characterized by a higher comorbidity prevalence. In the Cox multivariate
analysis, the initial BMI, evaluated as a continuous variable continued to be an independent predictor of
delayed graft function and chronic nephropathy. This study evaluated the BMI as a continuous value
instead of a categorical value. In conclusion, our results suggest that an increase in BMI without
categorical variation can be an independent risk factor for graft loss. Consequently, obesity prevention
for renal transplant patients should include dietary counseling and management, moderate physical
activity, and steroid minimization.},
publisher = {Ivyspring International Publisher},
keywords = {Anthropometry},
keywords = {Obesity},
keywords = {BMI},
keywords = {Graft Loss},
keywords = {Kidney transplantation},
keywords = {Overweight},
title = {Study of weight and body mass index on graft loss after transplant over 5 years of evolution},
doi = {10.7150/ijms.47000},
author = {Liñán González, Antonio and García Pérez, Raquel and Bravo Soto, Juan and Fernández Castillo, Rafael},
}