@misc{10481/63417,
year = {2020},
month = {7},
url = {http://hdl.handle.net/10481/63417},
abstract = {Peru is one of the main areas where there are large cocoa crops with special relevance to
the economy of this country. In fact, cocoa is a major, economically important, international crop
which has been linked to several benefits, such as anti-allergenic, anti-atherogenic, anti-inflammatory,
anti-microbial, anti-oxidant, anti-thrombotic, cardioprotective and vasodilatory properties, relating
to its bioactive compound content. However, in cocoa industrial processing, several residues or
wastes, which are commonly discarded generating a negative impact on the environment, are
produced in large amounts. Some of the cocoa by-products, which go underutilized, could be a
good source of bioactive compounds with high utility for the development of innovative products
in nutraceutical, medical or pharmaceutical industries. For this reason, the aim of this study is to
qualitatively determine the phytochemical composition of husk and bean extracts from different
cocoa-growing areas and processes from Peru by high performance liquid chromatography coupled
to mass spectrometry. Furthermore, we aim to evaluate their phenolic and flavan-3-ol contents and
antioxidant capacities for the purpose of highlighting the potential of cocoa by-products from these
cultivars as functional ingredients. In total, 49 chemical compounds were detected in the analyzed
extracts. Comparing both husks and beans, bean extracts were characterized by high content in
flavonoids whereas husk extracts had a higher content of phenolic acids. The presence of these
compounds together with the bioactivity results suggest that these matrices may be further studied
for their revaluation in the development of high added-value products in nutraceutical, medical, and
pharmaceutical industries.},
organization = {Ministry of Science, Innovation and Universities 	
RTI2018-096724-B-C22},
organization = {Spanish Ministry of Economy and Competitiveness (MINECO) 	
BES-2016-076618},
organization = {Ministry of Science, Innovation and Universities},
organization = {AGR274 group 	
5450},
organization = {University of Granada},
publisher = {MDPI},
keywords = {Cocoa},
keywords = {Polyphenols},
keywords = {LC–MS},
keywords = {By-products},
keywords = {Food waste},
keywords = {Revalorization},
keywords = {Antioxidant},
title = {LC-MS and Spectrophotometric Approaches for Evaluation of Bioactive Compounds from Peru Cocoa By-Products for Commercial Applications},
doi = {doi:10.3390/molecules25143177},
author = {Cádiz Gurrea, María de la Luz and Fernández Ochoa, Álvaro and Leyva Jiménez, Francisco Javier and Guerrero Muñoz, Noelia and Villegas Aguilar, María del Carmen and Pimentel Moral, Sandra and Segura Carretero, Antonio},
}