@misc{10481/63287,
year = {2020},
month = {5},
url = {http://hdl.handle.net/10481/63287},
abstract = {Catalase is a powerful antioxidant metalloenzyme located in peroxisomes which also plays a central role in
signaling processes under physiological and adverse situations. Whereas animals contain a single catalase gene,
in plants this enzyme is encoded by a multigene family providing multiple isoenzymes whose number varies
depending on the species, and their expression is regulated according to their tissue/organ distribution and the
environmental conditions. This enzyme can be modulated by reactive oxygen and nitrogen species (ROS/RNS) as
well as by hydrogen sulfide (H2S). Catalase is the major protein undergoing Tyr-nitration [post-translational
modification (PTM) promoted by RNS] during fruit ripening, but the enzyme from diverse sources is also susceptible to undergo other activity-modifying PTMs. Data on S-nitrosation and persulfidation of catalase from
different plant origins are given and compared here with results from obese children where S-nitrosation of
catalase occurs. The cysteine residues prone to be S-nitrosated in catalase from plants and from bovine liver have
been identified. These evidences assign to peroxisomes a crucial statement in the signaling crossroads among
relevant molecules (NO and H2S), since catalase is allocated in these organelles. This review depicts a scenario
where the regulation of catalase through PTMs, especially S-nitrosation and persulfidation, is highlighted.},
organization = {European Union (EU)},
organization = {Spanish Government

AGL2015-65104-P
PID2019103924GB-I00},
organization = {Plan Andaluz de Investigacion, Desarrollo e Innovacion 	
P18-FR-1359},
organization = {Junta de Andalucia

BIO 192},
organization = {Health Strategy Action (Spain's National Plan for Science and Technology Research, Development and Innovation) 	
PI18-01316},
publisher = {Elsevier},
keywords = {Docking},
keywords = {Nitration},
keywords = {S-nitrosation},
keywords = {Persulfidation},
keywords = {Post-translational modification},
keywords = {Signaling},
title = {Plant catalases as NO and H2S targets},
doi = {10.1016/j.redox.2020.101525},
author = {Palma, José Manuel and López Jaramillo, Francisco Javier and González Gordo, Salvador and Corpas, Francisco J.},
}