@misc{10481/63190,
year = {2020},
month = {6},
url = {http://hdl.handle.net/10481/63190},
abstract = {Background
To identify and quantify associations between baseline characteristics on hospital admission and mortality in patients with COVID-19 at a tertiary hospital in Spain.
Methods and findings
This retrospective case series included 238 patients hospitalized for COVID-19 at Hospital
Universitario Clı´nico San Cecilio (Granada, Spain) who were discharged or who died. Electronic medical records were reviewed to obtain information on sex, age, personal antecedents, clinical features, findings on physical examination, and laboratory results for each
patient. Associations between mortality and baseline characteristics were estimated as hazard ratios (HR) calculated with Cox regression models.
Series mortality was 25.6%. Among patients with dependence for basic activities of daily
living, 78.7% died, and among patients residing in retirement homes, 80.8% died. The variables most clearly associated with a greater hazard of death were age (3% HR increase per
1-year increase in age; 95%CI 1–6), diabetes mellitus (HR 2.42, 95%CI 1.43–4.09), SatO2/
FiO2 ratio (43% HR reduction per 1-point increase; 95%CI 23–57), SOFA score (19% HR
increase per 1-point increase, 95%CI 5–34) and CURB-65 score (76% HR increase per 1-
point increase, 95%CI 23–143).
Conclusions
The patients residing in retirement homes showed great vulnerability. The main baseline
factors that were independently associated with mortality in patients hospitalized for
COVID-19 were older age, diabetes mellitus, low SatO2/FiO2 ratio, and high SOFA and
CURB-65 scores.},
organization = {Fondos Estructurales de la Union Europea (FEDER)},
organization = {Unit of Excellence on Exercise and Health (UCEES), University of Granada},
publisher = {Public Library of Science},
keywords = {COVID-19},
title = {Sociodemographic, clinical and laboratory factors on admission associated with COVID19 mortality in hospitalized patients: A retrospective observational study},
doi = {10.1371/journal.pone.0235107},
author = {Rivera Izquierdo, Mario and Valero Ubierna, María del Carmen and Sánchez Pérez, María Rosa and Mancera Romero, José and García Martín, Miguel Ángel and Martín de los Reyes, Luis Miguel and Martínez Ruiz, Virginia Ana and Lardelli Claret, Pablo and Jiménez Mejías, Eladio},
}