@misc{10481/63106,
year = {2020},
month = {4},
url = {http://hdl.handle.net/10481/63106},
abstract = {Atherogenic index of plasma (AIP) is a novel biomarker related to cardiovascular disease
(CVD). Cardiorespiratory fitness (CRF) and physical activity (PA) have an inverse relationship with
the AIP, while sedentary time (ST) and fatness present a positive association. This study aimed to
determine the combined and independent association of CRF, PA, and ST with the AIP, and additionally
to establish the waist-to-height ratio (WHtR) mediation role. Data from the Chilean national health
survey were used (4671 adults). A PACS (Physical Activity Cardiorespiratory Sedentary) score was
created ranging from 0 to 3, indicating the number of positive recommendations met (PA, ST, and
CRF). AIP was calculated (Log10 triglycerides/high-density lipoprotein-cholesterol). The combined
analysis showed that compared to those with a PACS score of 0, those with a score of 1 or 2 did not
present significantly reduced AIP values (adjusted by the WHtR); however, those with a score of
3 did (OR (odds ratio) = 0.50; 95% CI, 0.32 to 0.77; p < 0.001). Independent analysis showed that
CRF seems to be the only variable that supports the combined result (β = −0.212; p < 0.001). Finally,
the mediation analysis indicated that the WHtR mediated the association between CRF and the AIP in
34.2% of cases. Overall, only CRF had a significant and inverse association with the AIP. Nonetheless,
around one-third of this beneficial relationship is affected by an elevated WHtR.},
organization = {Spanish Government

CTQ2017-87076-R},
publisher = {MDPI},
keywords = {Adiposity},
keywords = {Cardiovascular risk},
keywords = {Epidemiology},
keywords = {Healthy lifestyles},
keywords = {Lipid profile},
title = {Cardiorespiratory Fitness, Physical Activity, Sedentary Time and Its Association with the Atherogenic Index of Plasma in Chilean Adults: Influence of the Waist Circumference to Height Ratio},
doi = {10.3390/foods9050636},
author = {Reyes Ferrada, Waleska and Plaza Díaz, Julio and Solis-Urra, Patricio},
}