@misc{10481/63031, year = {2020}, url = {http://hdl.handle.net/10481/63031}, abstract = {Neck circumference (NC) has been proposed as a simple and practical tool, independently associated with cardiometabolic risk factors. However, the association of NC with inter-muscular adipose tissue (IMAT) is still to be determined. We aimed to examine the association of NC with thigh IMAT, and visceral adipose tissue (VAT) measured with computed tomography (CT) in overweight/obese women. 142 premenopausal overweight and obese Caucasian women participated in this crosssectional study. NC was measured with an inextensible metallic tape above the thyroid cartilage according to International Society for Advancement of Kinanthropometry protocol. Thigh IMAT and VAT volumes were measured with a single cross-sectional CT. Regarding the covariates, fat mass (FM) was assessed with dual-energy x-ray absorptiometry and physical activity was objectively measured with accelerometry. NC was positively associated with thigh IMAT and VAT volumes (standardized β coefcient: β=0.45, P-value= ≤0.001, β=0.60, P=≤0.001; respectively), which persisted after adjusting for age, height, overall FM or moderate-to-vigorous physical activity. Our fndings show that NC is associated with thigh IMAT volume in overweight and obese premenopausal Caucasian women, regardless of the amount of lower-body fatness. These results suggest underscoring the relevance of NC as a marker of adipose tissue content in thigh skeletal muscle.}, organization = {Portuguese Foundation for Science and Technology Sapiens 358007/99}, organization = {Oeiras City Council}, organization = {Becel Portugal}, organization = {Roche Pharmaceuticals Portugal}, organization = {Compal Portugal}, organization = {University of Granada Plan Propio de Investigacion 2016 -Excellence actions: Unit of Excellence on Exercise and Health (UCEES)}, organization = {Junta de Andalucia}, organization = {European Union (EU) SOMM17/6107/UGR}, organization = {Fundacion Carolina C.2016574961}, publisher = {Nature Research (part of Springer Nature)}, title = {Neck circumference is associated with adipose tissue content in thigh skeletal muscle in overweight and obese premenopausal women}, doi = {10.1038/s41598-020-65204-9}, author = {Arias Téllez, María José and Ruiz Ruiz, Jonatan}, }