@misc{10481/62467,
year = {2020},
month = {4},
url = {http://hdl.handle.net/10481/62467},
abstract = {Normal-weight obesity (NWO) has been shown to be associated with cardiometabolic
dysfunction. However, little is known regarding this potential relationship in early adulthood.
The aim of this study was to investigate the associations between NWO and cardiometabolic risk
factors in a large population of Colombian young adults. A cross-sectional study was conducted on
1354 subjects (61% women), aged from 18 to 30. Anthropometric data, including body mass index
(BMI) and waist circumference (WC), were estimated, and the percentage of fat mass was measured
through bioelectrical impedance analysis (BIA). Muscular fitness was determined by using a handgrip
strength test and normalized grip strength (NGS = handgrip (kg)/body mass (kg)). A cardiometabolic
risk Z-score was derived by assessing WC, triglycerides, high-density lipoprotein cholesterol (HDL-C)
cholesterol, fasting glucose, and systolic blood pressure. NWO was defined by the combination of
excess %BF (over 25.5% for men and 38.9% for women) and a BMI < 25 kg/m2
. The overall prevalence
of NWO was 29.1%. Subjects with NWO have an increased risk of cardiometabolic risk compared to
the normal-weight lean group (OR = 3.10). Moreover, NWO was associated with an increased risk of
presenting low HDL-C (OR = 2.34), high abdominal obesity (OR = 7.27), and low NGS (OR = 3.30),
p < 0.001. There is a high prevalence of NWO in American Latin young adults and this condition is
associated with an increased cardiovascular risk, high blood pressure, low HDL-C, high abdominal
obesity, and low muscular strength early in life. Screening for adiposity in subjects with a normal
BMI could help to identify young adults at a high risk of cardiometabolic abnormalities.},
organization = {This study was part of the project entitled “Body Adiposity Index and Biomarkers of Endothelial and
Cardiovascular Health in Adults” (Code N FIUR DN-BG001), Institución Universitaria Antonio José Camacho
(Code N 111-02.01.48/16), Universidad Santo Tomás (Code N 2013004), Universidad Manuela Beltrán (Code N
FT201204), and Universidad de Boyacá (Code N RECT 60). M.I. is funded in part by a research grant PI17/01814 of
the Ministerio de Economía, Industria y Competitividad de España (ISCIII, FEDER). A.G.-H. is a Miguel Servet
Fellow (Instituto de Salud Carlos III—CP18/0150). R.R.-V. is funded in part by a Postdoctotal fellowship grant ID
420/2019 of the Universidad Pública de Navarra, Spain. The funder had no role in the study design, data collection,
data analysis and interpretation, preparation of the manuscript, or decision to publish.},
publisher = {MDPI},
keywords = {Body composition},
keywords = {Normal-weight obesity},
keywords = {Body fat},
keywords = {Cardiometabolic risk},
keywords = {Young adults},
title = {Normal-Weight Obesity Is Associated with Increased Cardiometabolic Risk in Young Adults},
doi = {doi:10.3390/nu12041106},
author = {Correa Rodríguez, María},
}