@misc{10481/62420,
year = {2020},
month = {2},
url = {http://hdl.handle.net/10481/62420},
abstract = {The importance of gut microbiota in health and disease is being highlighted by numerous
research groups worldwide. Atherosclerosis, the leading cause of heart disease and stroke,
is responsible for about 50% of all cardiovascular deaths. Recently, gut dysbiosis has been identified
as a remarkable factor to be considered in the pathogenesis of cardiovascular diseases (CVDs). In this
review, we briefly discuss how external factors such as dietary and physical activity habits influence
host-microbiota and atherogenesis, the potential mechanisms of the influence of gut microbiota in
host blood pressure and the alterations in the prevalence of those bacterial genera affecting vascular
tone and the development of hypertension. We will also be examining the microbiota as a therapeutic
target in the prevention of CVDs and the beneficial mechanisms of probiotic administration related to
cardiovascular risks. All these new insights might lead to novel analysis and CVD therapeutics based
on the microbiota.},
publisher = {MDPI},
keywords = {Cardiovascular diseases},
keywords = {Atherosclerosis},
keywords = {Gut microbiota},
keywords = {Microbiome},
title = {The Gut Microbiota and Its Implication in the Development of Atherosclerosis and Related Cardiovascular Diseases},
doi = {doi:10.3390/nu12030605},
author = {Sanchez-Rodriguez, Estefania and Egea Zorrilla, Alejandro and Plaza Díaz, Julio and Abadía Molina, Francisco},
}