@misc{10481/62073,
year = {2019},
month = {6},
url = {http://hdl.handle.net/10481/62073},
abstract = {The effect of dietary fat intake on the metabolic syndrome (MetS) and in
turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective:
To assess the association between fat intake and MetS components in an adult Mediterranean
population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants
(n = 6560, men and women, 55–75 years old, with overweight/obesity and MetS) in the PREvención
con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake
(total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids:
SFA, trans-fatty acids: trans-FA, linoleic acid, a-linolenic acid, and w-3 FA) using a validated food
frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat
quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed
lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA,
LA, ALA and !-3 FA. Differences in MetS components were found according to fat intake. Odds (5th
vs. 1st quintile): hyperglycemia: 1.3–1.6 times higher for total fat, MUFA, SFA and w-3 FA intake; low
high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for
SFA and w-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high
CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.},
organization = {The PREDIMED-Plus trial was supported by the official funding agency for biomedical research of the
Spanish government, ISCIII through the Fondo de Investigación para la Salud (FIS), which is co-funded by the
European Regional Development Fund (four coordinated FIS projects led by Jordi Salas-Salvadó and Josep Vidal,
including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184,
PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919,
PI14/00853, PI14/01374, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381,
PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827,
PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926), the Especial Action Project entitled:
Implementación y evaluación de una intervención intensive sobre la actividad física Cohorte PREDIMED-PLUS
grant to Jordi Salas-Salvadó, the European Research Council (Advanced Research Grant 2013-2018; 340918) grant to
Miguel Ángel Martínez-Gonzalez, the Recercaixa grant to Jordi Salas-Salvadó (2013ACUP00194), grants from the
Consejería de Salud de la Junta de Andalucía (PI0458/2013; PS0358/2016; PI0137/2018), the PROMETEO/2017/017
grant from the Generalitat Valenciana, the SEMERGEN grant, and CIBEROBN and FEDER funds (CB06/03),
ISCIII. International Nut & Dried Fruit Council – FESNAD No. 201302: Miguel Ángel Martínez-Gonzalez (PI).
Alicia Julibert, Maria del Mar Bibiloni, Cristina Bouzas, Lucía Ugarriza and Josep A. Tur are granted by Grant
of support to research groups no. 35/2011 (Balearic Islands Gov.; FEDER funds), EU-COST ACTION CA16112,
and Fundació La Marató TV3 (Spain) project ref. 201630.10.},
publisher = {MDPI},
keywords = {Fatty acids},
keywords = {Dietary fat},
keywords = {Fat intake},
keywords = {Mediterranean diet},
keywords = {Cardiovascular disease risk},
title = {Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk},
author = {Julibert, Alicia and García Molina, Laura},
}